TY - CHAP
T1 - Vascular Endothelial Growth Factors in Tissue Engineering
T2 - Challenges and Prospects for Therapeutic Angiogenesis
AU - Lifirsu, Ekaterina S.
AU - Ramalingam, Murugan
AU - Haidar, Ziyad S.
PY - 2012/4/4
Y1 - 2012/4/4
N2 - Technologies enhancing tissue vascularity are critically important to cardiovascular medicine. Currently, strategies to promote angiogenesis and arteriogenesis in a controlled manner are limited. This chapter discusses the role and promise of vascular endothelial growth factor (VEGF), in hard/soft tissue engineering applications, primarily focusing on therapeutic angiogenesis. A brief review of the different delivery systems, ranging from scaffolds to nanoparticles, carrying VEGF follows, in the context of present potential and challenges. Finally, a prospectus on the future of VEGF therapy will be presented.
AB - Technologies enhancing tissue vascularity are critically important to cardiovascular medicine. Currently, strategies to promote angiogenesis and arteriogenesis in a controlled manner are limited. This chapter discusses the role and promise of vascular endothelial growth factor (VEGF), in hard/soft tissue engineering applications, primarily focusing on therapeutic angiogenesis. A brief review of the different delivery systems, ranging from scaffolds to nanoparticles, carrying VEGF follows, in the context of present potential and challenges. Finally, a prospectus on the future of VEGF therapy will be presented.
KW - Hard tissues
KW - Soft tissues
KW - Therapeutic angiogenesis
KW - Tissue engineering
KW - Vascular endothelial growth factors
UR - http://www.scopus.com/inward/record.url?scp=84887145175&partnerID=8YFLogxK
U2 - 10.1002/9781118371183.ch11
DO - 10.1002/9781118371183.ch11
M3 - Chapter
AN - SCOPUS:84887145175
SN - 9781118311981
SP - 275
EP - 293
BT - Integrated Biomaterials in Tissue Engineering
PB - John Wiley and Sons
ER -