Technical and economic analysis of industrial production of lactose-derived prebiotics with focus on galacto-oligosaccharides

Felipe Scott*, Carlos Vera, Raúl Conejeros

*Autor correspondiente de este trabajo

Producción científica: Capítulo del libro/informe/acta de congresoCapítulorevisión exhaustiva

17 Citas (Scopus)


Galactooligosaccharides (GOS) are the most relevant prebiotics synthesized from lactose. During the last decades, a number of processes have been reported for its industrial production using β-galactosidase as catalyst. However, economic and technical analyses are seldom published. This chapter analyzes a number of processes for GOS production considering two sources of β-galactosidase and several purification strategies from a technical and economic point of view. Among the purification alternatives, simulated moving bed chromatography and removal of unwanted mono and disaccharides by bioconversion with yeast are included. Process alternatives are compared within a common price framework using the minimum product selling price. Results show that the calculated minimum selling prices are well below the market prices for GOS, thus leaving room for marketing and distribution costs. Furthermore, the integration of GOS production to an existing dairy industry is analyzed focusing in plant capacity, installed equipment and market lactose and whey prices.

Idioma originalInglés
Título de la publicación alojadaLactose-Derived Prebiotics
Subtítulo de la publicación alojadaA Process Perspective
EditorialElsevier Inc.
Número de páginas24
ISBN (versión digital)9780128027455
ISBN (versión impresa)9780128027240
EstadoPublicada - 7 jul. 2016

Nota bibliográfica

Publisher Copyright:
© 2016 Elsevier Inc. All rights reserved.

Palabras clave

  • Investment costs
  • Operational costs
  • Prebiotics minimum selling price
  • Prebiotics techno-economic analysis
  • Selective fermentations
  • Simulated moving bed chromatography


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