Successful treatment of thrombotic thrombocytopenic purpura with vincristine report of one case

Francisco Espinoza, José Luis Leal Fernández, Guillermo Arenas

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)

Resumen

Thrombotic thrombocytopenic purpura presents as a multisystemic disease with thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological and renal involvement. We report a 24 years-old male presenting with purpura and a generalized seizure. His blood tests showed an hemolytic anemia, unconjungated hyperbilirubinemia, increased lactated dehydrogenase, thrombocytopenia and impairment of renal function. He was initially treated with daily plasmapheresis and steroids without improvement. Due to persistence of the disease, he was treated with two doses of intravenous vincristine in four days, with clinical and laboratory improvement. He was discharged 40 days after the last dose of vincristine, in good conditions.
Idioma originalInglés estadounidense
Páginas (desde-hasta)1572-1576
Número de páginas5
PublicaciónRevista Medica de Chile
Volumen135
N.º12
EstadoPublicada - 1 dic 2007

Palabras clave

  • Purpura, thrombocytopenic
  • Purpura, thrombotic thrombocytopenic
  • Vincristine

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