Sistemas de nanopartículas poliméricas ii: Estructura, métodos de elaboración, características, propiedades, biofuncionalización y tecnologías de auto-ensamblaje capa por capa (layer-by-layer self-assembly)

Madelein C. Urrejola, Liliam V. Soto, Consuelo C. Zumarán, Juan Pablo Peñaloza, Beatriz Álvarez, Ignacio Fuentevilla, Ziyad S. Haidar*

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

7 Citas (Scopus)

Resumen

SUMMARY: Polymeric materials have been extensively investigated for biomedical applications including micro-and nanoparticles. Modern advances have broadened horizons for application with peptides and nucleic acids. Therefore, interests increased in the formulation of materials, devices and vehicles for transporting therapeutic agents in functionalized nanostructures. Recent nano-systems are inspired by natural phenomena that stimulate the integration of molecular signals and the mimicking of natural cellular processes, at tissue and organ levels. Technologically, the ability to obtain spherical nanostructures, which combine different properties, that no other single material possesses on its own, makes nanocapsules particularly attractive. Potential advantages over polymer nanoparticulate systems are highlighted throughout each part of this review article. Here, we address the most relevant aspects of structure, composition and methods of formulation of nanoparticulate systems. In addition, we outline some of the more recent works focusing on nanosized preparations, based on agent-directed polymers, found in specialized research articles that have emerged in the recent years.
Título traducido de la contribuciónPolymeric nanoparticle systems: Structure, elaboration methods, characteristics, properties, biofunctionalization and self-assembly layer by layer technologies
Idioma originalEspañol
Páginas (desde-hasta)1463-1471
Número de páginas9
PublicaciónInternational Journal of Morphology
Volumen36
N.º4
DOI
EstadoPublicada - dic. 2018

Nota bibliográfica

Publisher Copyright:
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Palabras clave

  • Dendrimers
  • Nanocapsules
  • Nanospheres
  • Nanostructures
  • Quantum dots

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