Recomendaciones para la implementación en Chile de la genotipificación extendida para virus del papiloma humano en tamizaje y seguimiento

introduction: Most cases of cervical cancer occur in women without current screening (either due to lack of coverage or adherence to prevention programs) and/or poor screening (it is estimated that one in three women with cancer had a current Papanicolau screening). Local epidemiological data regarding human papillomavirus (HPV), its causal agent, is scarce and the availability of resources such as HPV-polymerase chain reaction (PCR) test and colposcopy are very limited. objective: Generate recommendations that allow optimizing the cost-effectiveness of HPV-PCR screening and follow-up. Material and methods: A critical review of scientific articles and clinical guidelines, both national and foreign, is carried out, and recommendations compatible with current national guidelines are prepared by consensus of a multidisciplinary panel of specialists.Results: A guide of recommendations which includes work algorithms and reporting model for the implementation of screening and follow-up based on HPV-PCR with extended genotyping. Conclusions: The implementation of extended genotyping allows the development of a cost-effective strategy based on stratification and monitoring according to oncogenic risk, a comprehensive concept that helps prevent overtreatment, giving the possibility of redistributing resources and reducing cancer.