TY - JOUR
T1 - Osteonecrosis de los maxilares asociada a medicamentos
T2 - Revisión de la literatura y propuesta para la prevención y manejo
AU - Foncea, Camila
AU - von Bischhoffshausen, Kristine
AU - Teuber, Cristián
AU - Ramírez, Hernán
AU - Goñi, Ignacio
AU - Sánchez, Cesar
AU - Retamal, Ignacio N.
AU - Vargas, Alex
N1 - Publisher Copyright:
© 2020 Sociedad Medica de Santiago. All rights reserved.
PY - 2020/7
Y1 - 2020/7
N2 - Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.
AB - Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.
KW - Angiogenesis Inhibitors
KW - Bisphosphonate-Associated Osteonecrosis of the Jaw
KW - Bone Density Conservation Agents
KW - Diphosphonates
KW - Osteonecrosis
UR - http://www.scopus.com/inward/record.url?scp=85095129788&partnerID=8YFLogxK
U2 - 10.4067/S0034-98872020000700983
DO - 10.4067/S0034-98872020000700983
M3 - Review article
C2 - 33399683
AN - SCOPUS:85095129788
SN - 0034-9887
VL - 148
SP - 983
EP - 991
JO - Revista Medica de Chile
JF - Revista Medica de Chile
IS - 7
ER -