Nutritional phases of prader-willi syndrome

Prader-Willi Syndrome (PWS) is the most common cause of genetic obesity. Hyperphagia and obesity are the most associated concepts with this condition. However, undernutrition secondary to severe hypotonia and feeding difficulties is the predominant initial feature. Objective: to reproduce and communicate the nutritional phases on a series of Chilean cases with PWS. Patients and Method: Cross-sectional study in which clinical records of PWS individuals under nutritional control at the Clínica Santa María in Santiago, Chile between 2017 and 2018 were analyzed. The anthropometric references of the World Health Organization were used to carry out the nutritional assessment. The classification into nutritional phases was according to the Miller criteria. Results: 24 patients from infants to adults were included. All children aged under 9 months were in phase I and had malnutrition or were eutrophic; those between 9 and 25 months were classified in phase 2a; patients between 2.1 and 4.5 years were distributed between phases 1 and 2 and 66% were eutrophic; those between 4.5 to 8 years, 80% were in phase 2a and 2b and obesity begins to appear, and patients over 8 years of age, 75% were in phase 3 and all are overweight or obese. There was an association between nutritional phase and age but not between it and nutritional status. Conclusions: In our series, the nutritional phases described according to age were reproduced according to those internationally described. There was no association between nutritional status and age.