Microtechnology applied to stem cells research and development

Juan Pablo Acevedo*, Ioannis Angelopoulos, Danny Van Noort, Maroun Khoury

*Autor correspondiente de este trabajo

Resultado de la investigación: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

1 Cita (Scopus)

Resumen

Microfabrication and microfluidics contribute to the research of cellular functions of cells and their interaction with their environment. Previously, it has been shown that microfluidics can contribute to the isolation, selection, characterization and migration of cells. This review aims to provide stem cell researchers with a toolkit of microtechnology (mT) instruments for elucidating complex stem cells functions which are challenging to decipher with traditional assays and animal models. These microdevices are able to investigate about the differentiation and niche interaction, stem cells transcriptomics, therapeutic functions and the capture of their secreted microvesicles. In conclusion, microtechnology will allow a more realistic assessment of stem cells properties, driving and accelerating the translation of regenerative medicine approaches to the clinic.

Idioma originalInglés
Páginas (desde-hasta)233-248
Número de páginas16
PublicaciónRegenerative Medicine
Volumen13
N.º2
DOI
EstadoPublicada - mar. 2018

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© 2018 2018 Future Medicine Ltd.

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