Maternal serum transformed α-fetoprotein levels in women with intrauterine growth retardation

Jose L. Bartha; Sebastian Illanes; Fernando González-Bugatto; Sherif A. Abdel-Fattah; Gerald J. Mizejewski; Peter W. Soothill

doi:10.1159/000100794

Maternal serum transformed α-fetoprotein levels in women with intrauterine growth retardation

Jose L. Bartha, Sebastian Illanes, Fernando González-Bugatto, Sherif A. Abdel-Fattah, Gerald J. Mizejewski, Peter W. Soothill

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

8 Citas (Scopus)

Resumen

Objective: To evaluate maternal serum transformed α-fetoprotein (t-AFP) levels in women with intrauterine growth retardation (IUGR). Methods: 60 pregnant women in two groups were studied: 30 with IUGR and 30 healthy pregnant women as a control group. t-AFP concentrations were determined by ELISA assay. Results: Maternal serum t-AFP levels were higher in women with IUGR than in the control group: 15.39 (10.81-24.01) ng/ml vs. 8.66 (6.22-13.45) ng/ml (p = 0.003). t-AFP levels were even higher in those with fetal hemodynamic redistribution 21.08 (16.02-40.85) ng/ml than in those without 12.15 (10.48-17.45) ng/ml (p = 0.03). Conclusions: Maternal serum t-AFP is increased in women with IUGR and this elevation is marked in those with fetal hemodynamic redistribution. Copyright

Idioma original	Inglés estadounidense
Páginas (desde-hasta)	294-298
Número de páginas	5
Publicación	Fetal Diagnosis and Therapy
Volumen	22
N.º	4
DOI	https://doi.org/10.1159/000100794
Estado	Publicada - 1 jun. 2007
Publicado de forma externa	Sí

Palabras clave

α-Fetoprotein
Growth retardation
Pregnancy complications

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title = "Maternal serum transformed α-fetoprotein levels in women with intrauterine growth retardation",

abstract = "Objective: To evaluate maternal serum transformed α-fetoprotein (t-AFP) levels in women with intrauterine growth retardation (IUGR). Methods: 60 pregnant women in two groups were studied: 30 with IUGR and 30 healthy pregnant women as a control group. t-AFP concentrations were determined by ELISA assay. Results: Maternal serum t-AFP levels were higher in women with IUGR than in the control group: 15.39 (10.81-24.01) ng/ml vs. 8.66 (6.22-13.45) ng/ml (p = 0.003). t-AFP levels were even higher in those with fetal hemodynamic redistribution 21.08 (16.02-40.85) ng/ml than in those without 12.15 (10.48-17.45) ng/ml (p = 0.03). Conclusions: Maternal serum t-AFP is increased in women with IUGR and this elevation is marked in those with fetal hemodynamic redistribution. Copyright",

keywords = "α-Fetoprotein, Growth retardation, Pregnancy complications, α-Fetoprotein, Growth retardation, Pregnancy complications",

author = "Bartha, {Jose L.} and Sebastian Illanes and Fernando Gonz{\'a}lez-Bugatto and Abdel-Fattah, {Sherif A.} and Mizejewski, {Gerald J.} and Soothill, {Peter W.}",

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doi = "10.1159/000100794",

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AU - Bartha, Jose L.

AU - Illanes, Sebastian

AU - González-Bugatto, Fernando

AU - Abdel-Fattah, Sherif A.

AU - Mizejewski, Gerald J.

AU - Soothill, Peter W.

PY - 2007/6/1

Y1 - 2007/6/1

N2 - Objective: To evaluate maternal serum transformed α-fetoprotein (t-AFP) levels in women with intrauterine growth retardation (IUGR). Methods: 60 pregnant women in two groups were studied: 30 with IUGR and 30 healthy pregnant women as a control group. t-AFP concentrations were determined by ELISA assay. Results: Maternal serum t-AFP levels were higher in women with IUGR than in the control group: 15.39 (10.81-24.01) ng/ml vs. 8.66 (6.22-13.45) ng/ml (p = 0.003). t-AFP levels were even higher in those with fetal hemodynamic redistribution 21.08 (16.02-40.85) ng/ml than in those without 12.15 (10.48-17.45) ng/ml (p = 0.03). Conclusions: Maternal serum t-AFP is increased in women with IUGR and this elevation is marked in those with fetal hemodynamic redistribution. Copyright

AB - Objective: To evaluate maternal serum transformed α-fetoprotein (t-AFP) levels in women with intrauterine growth retardation (IUGR). Methods: 60 pregnant women in two groups were studied: 30 with IUGR and 30 healthy pregnant women as a control group. t-AFP concentrations were determined by ELISA assay. Results: Maternal serum t-AFP levels were higher in women with IUGR than in the control group: 15.39 (10.81-24.01) ng/ml vs. 8.66 (6.22-13.45) ng/ml (p = 0.003). t-AFP levels were even higher in those with fetal hemodynamic redistribution 21.08 (16.02-40.85) ng/ml than in those without 12.15 (10.48-17.45) ng/ml (p = 0.03). Conclusions: Maternal serum t-AFP is increased in women with IUGR and this elevation is marked in those with fetal hemodynamic redistribution. Copyright

KW - α-Fetoprotein

KW - Growth retardation

KW - Pregnancy complications

KW - α-Fetoprotein

KW - Growth retardation

KW - Pregnancy complications

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Maternal serum transformed α-fetoprotein levels in women with intrauterine growth retardation

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