Leucocyte- and platelet-rich fibrin block for bone augmentation procedure: A proof-of-concept study

Simone Cortellini*, Ana B. Castro, Andy Temmerman, Jeroen Van Dessel, Nelson Pinto, Reinhilde Jacobs, Marc Quirynen

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

55 Citas (Scopus)


The objective of this proof-of-concept study was to investigate the effects of a new guided bone regeneration technique with a tissue engineering approach.

Materials and Methods
This single cohort observational study evaluated the outcome of the leucocyte- and platelet-rich fibrin (L-PRF) Block for horizontal bone augmentation in the maxilla. The L-PRF Block is prepared by mixing a particulated biomaterial with chopped L-PRF membranes at a 50:50 ratio and adding liquid fibrinogen to glue all together. Horizontal augmentation was assessed linearly and volumetrically immediately after surgery and 5–8 months later by matching consecutive cone beam computed tomography (CBCTs).

Ten patients (mean age of 50.7 years [±17.2]) representing 15 sites with horizontal alveolar deficiencies were included. Superimposition of pre-operative and posthealing CBCT scans showed an average linear horizontal bone gain of 4.6 mm (±2.3), 5.3 mm (±1.2) and 4.4 mm (±2.3), measured at 2, 6 and 10 mm from the alveolar crest, respectively. The volumetric gain was 1.05 cm3 (±0.7) on average. The resorption rate after 5–8 months was 15.6% (±6.7) on average.

L-PRF Block may be a suitable technique to augment deficient alveolar ridges.
Idioma originalInglés
Páginas (desde-hasta)624-634
Número de páginas11
PublicaciónJournal of Clinical Periodontology
EstadoPublicada - may. 2018

Nota bibliográfica

Publisher Copyright:
© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd


Profundice en los temas de investigación de 'Leucocyte- and platelet-rich fibrin block for bone augmentation procedure: A proof-of-concept study'. En conjunto forman una huella única.

Citar esto