Resumen
Aim
The objective of this proof-of-concept study was to investigate the effects of a new guided bone regeneration technique with a tissue engineering approach.
Materials and Methods
This single cohort observational study evaluated the outcome of the leucocyte- and platelet-rich fibrin (L-PRF) Block for horizontal bone augmentation in the maxilla. The L-PRF Block is prepared by mixing a particulated biomaterial with chopped L-PRF membranes at a 50:50 ratio and adding liquid fibrinogen to glue all together. Horizontal augmentation was assessed linearly and volumetrically immediately after surgery and 5–8 months later by matching consecutive cone beam computed tomography (CBCTs).
Results
Ten patients (mean age of 50.7 years [±17.2]) representing 15 sites with horizontal alveolar deficiencies were included. Superimposition of pre-operative and posthealing CBCT scans showed an average linear horizontal bone gain of 4.6 mm (±2.3), 5.3 mm (±1.2) and 4.4 mm (±2.3), measured at 2, 6 and 10 mm from the alveolar crest, respectively. The volumetric gain was 1.05 cm3 (±0.7) on average. The resorption rate after 5–8 months was 15.6% (±6.7) on average.
Conclusions
L-PRF Block may be a suitable technique to augment deficient alveolar ridges.
The objective of this proof-of-concept study was to investigate the effects of a new guided bone regeneration technique with a tissue engineering approach.
Materials and Methods
This single cohort observational study evaluated the outcome of the leucocyte- and platelet-rich fibrin (L-PRF) Block for horizontal bone augmentation in the maxilla. The L-PRF Block is prepared by mixing a particulated biomaterial with chopped L-PRF membranes at a 50:50 ratio and adding liquid fibrinogen to glue all together. Horizontal augmentation was assessed linearly and volumetrically immediately after surgery and 5–8 months later by matching consecutive cone beam computed tomography (CBCTs).
Results
Ten patients (mean age of 50.7 years [±17.2]) representing 15 sites with horizontal alveolar deficiencies were included. Superimposition of pre-operative and posthealing CBCT scans showed an average linear horizontal bone gain of 4.6 mm (±2.3), 5.3 mm (±1.2) and 4.4 mm (±2.3), measured at 2, 6 and 10 mm from the alveolar crest, respectively. The volumetric gain was 1.05 cm3 (±0.7) on average. The resorption rate after 5–8 months was 15.6% (±6.7) on average.
Conclusions
L-PRF Block may be a suitable technique to augment deficient alveolar ridges.
| Idioma original | Inglés |
|---|---|
| Páginas (desde-hasta) | 624-634 |
| Número de páginas | 11 |
| Publicación | Journal of Clinical Periodontology |
| Volumen | 45 |
| N.º | 5 |
| DOI | |
| Estado | Publicada - may. 2018 |
Nota bibliográfica
Publisher Copyright:© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd