TY - JOUR
T1 - L-prf for use in oro-maxillo-facial surgeries: What do we know?
T2 - what do we know?
AU - Muñoz, Francisco T.
AU - Haidar, Ziyad S.
N1 - Funding Information:
Acknowledgements: This work was carried out under onging collaboration between Universidad de los Andes and Lebanese University; supported by operating grants provided to BioMAT’X (Laboratorio de Biomateriales, Farmacéuticos y Bioingeniería de Tejidos Cráneo Máxilo-Facial), member of CIIB (Centro de Investigación e Innovación Biomédica), through the Faculty of Dentistry and PMI (Danilo Segovia, Anil Sadarangani and Silvana Becerra) Univ. los Andes, Santiago de Chile and CONICYT-FONDEF (Grant ID# 16I10366).
PY - 2018/3/27
Y1 - 2018/3/27
N2 - Précis - The art and science of oro-maxillo-facial reconstruction is of great interest for contemporary oral and maxillofacial surgeons; in search for better bioengineering strategies and biomaterials: a core driver for bio-dental research, today. Leukocyteand Platelet-Rich Fibrin (L-PRF) is a 3-D autogenous biomaterial obtained via the simple and rapid centrifugation of whole blood patient samples, in the absence of anti-coagulants, bovine thrombin, additives or any gelifying agents. A relatively new “revolutionary” step in 2nd generation platelet concentrate-based therapeutics, the clinical safety, and more so, efficacy and effectiveness of L-PRF remains highly debatable, whether due to significant variabilities in preparation protocols, limited evidence-based scientific and clinical literature and/or inadequate
AB - Précis - The art and science of oro-maxillo-facial reconstruction is of great interest for contemporary oral and maxillofacial surgeons; in search for better bioengineering strategies and biomaterials: a core driver for bio-dental research, today. Leukocyteand Platelet-Rich Fibrin (L-PRF) is a 3-D autogenous biomaterial obtained via the simple and rapid centrifugation of whole blood patient samples, in the absence of anti-coagulants, bovine thrombin, additives or any gelifying agents. A relatively new “revolutionary” step in 2nd generation platelet concentrate-based therapeutics, the clinical safety, and more so, efficacy and effectiveness of L-PRF remains highly debatable, whether due to significant variabilities in preparation protocols, limited evidence-based scientific and clinical literature and/or inadequate
UR - http://www.scopus.com/inward/record.url?scp=85044470447&partnerID=8YFLogxK
U2 - 10.17126/joralres.2018.012
DO - 10.17126/joralres.2018.012
M3 - Article
AN - SCOPUS:85044470447
SN - 0719-2479
VL - 7
SP - 88
EP - 90
JO - Journal of Oral Research
JF - Journal of Oral Research
IS - 3
ER -