Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results

C. von Muhlenbrock; P. Núñez; K. Herrera; N. Pacheco; R. Quera

doi:10.1016/j.rgmx.2025.03.001

Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results

Título traducido de la contribución: Trasplante de microbiota fecal mediante colonoscopia para el manejo del síndrome de intestino irritable refractario: resultados preliminares

C. von Muhlenbrock^*, P. Núñez, K. Herrera, N. Pacheco, R. Quera

^*Autor correspondiente de este trabajo

Clínica Universidad de los Andes

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Resumen

Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.

Título traducido de la contribución	Trasplante de microbiota fecal mediante colonoscopia para el manejo del síndrome de intestino irritable refractario: resultados preliminares
Idioma original	Inglés
Páginas (desde-hasta)	334-337
Número de páginas	4
Publicación	Revista de Gastroenterologia de Mexico
Volumen	90
N.º	2
DOI	https://doi.org/10.1016/j.rgmx.2025.03.001
Estado	Publicada - 1 abr. 2025

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© 2025 Asociación Mexicana de Gastroenterología

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title = "Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results",

abstract = "Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.",

keywords = "Colonoscopy, Fecal microbiota transplantation, Irritable bowel syndrome, Microbiota, Treatment",

author = "{von Muhlenbrock}, C. and P. N{\'u}{\~n}ez and K. Herrera and N. Pacheco and R. Quera",

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Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results. / von Muhlenbrock, C.; Núñez, P.; Herrera, K. et al.
En: Revista de Gastroenterologia de Mexico, Vol. 90, N.º 2, 01.04.2025, p. 334-337.

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

TY - JOUR

T1 - Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome

T2 - Preliminary results

AU - von Muhlenbrock, C.

AU - Núñez, P.

AU - Herrera, K.

AU - Pacheco, N.

AU - Quera, R.

PY - 2025/4/1

Y1 - 2025/4/1

N2 - Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.

AB - Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.

KW - Colonoscopy

KW - Fecal microbiota transplantation

KW - Irritable bowel syndrome

KW - Microbiota

KW - Treatment

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JF - Revista de Gastroenterologia de Mexico

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ER -

Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results

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