Colangitis esclerosante primaria y enfermedad inflamatoria intestinal: interrelación intestino-hígado

Paulina Núñez F.; Rodrigo Quera P.; Fernando Gomollón

doi:10.1016/j.gastrohep.2019.02.004

Colangitis esclerosante primaria y enfermedad inflamatoria intestinal: interrelación intestino-hígado

Paulina Núñez F.^*, Rodrigo Quera P., Fernando Gomollón

^*Autor correspondiente de este trabajo

Resultado de la investigación: Contribución a una revista › Artículo de revisión › revisión exhaustiva

13 Citas (Scopus)

Resumen

The association between inflammatory bowel disease (IBD)and primary sclerosing cholangitis should be considered a distinct clinical entity. This association involves genetic abnormalities, epidemiological factors (more common in men, with no a geographical pattern)and, commonly, subclinical inflammation, predominance of the right colon (endoscopic and histological), backwash ileitis and rectal sparing. Furthermore, there is an increased risk of colorectal cancer and cholangiocarcinoma. The aim of this review is to show how IBD influences the progression of this entity, transplantation requirements and recurrence. We also discuss the current evidence on the use of biological therapy in this group of patients.

Título traducido de la contribución	Primary sclerosing cholangitis and inflammatory bowel disease: Intestine-liver interrelation
Idioma original	Español
Páginas (desde-hasta)	316-325
Número de páginas	10
Publicación	Gastroenterologia y Hepatologia
Volumen	42
N.º	5
DOI	https://doi.org/10.1016/j.gastrohep.2019.02.004
Estado	Publicada - may. 2019
Publicado de forma externa	Sí

Nota bibliográfica

Publisher Copyright:
© 2019 Elsevier España, S.L.U.

Palabras clave

Crohn's disease
Inflammatory bowel disease
Primary sclerosing cholangitis
Ulcerative colitis

ODS de las Naciones Unidas

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10.1016/j.gastrohep.2019.02.004

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title = "Colangitis esclerosante primaria y enfermedad inflamatoria intestinal: interrelaci{\'o}n intestino-h{\'i}gado",

abstract = "The association between inflammatory bowel disease (IBD)and primary sclerosing cholangitis should be considered a distinct clinical entity. This association involves genetic abnormalities, epidemiological factors (more common in men, with no a geographical pattern)and, commonly, subclinical inflammation, predominance of the right colon (endoscopic and histological), backwash ileitis and rectal sparing. Furthermore, there is an increased risk of colorectal cancer and cholangiocarcinoma. The aim of this review is to show how IBD influences the progression of this entity, transplantation requirements and recurrence. We also discuss the current evidence on the use of biological therapy in this group of patients.",

keywords = "Crohn's disease, Inflammatory bowel disease, Primary sclerosing cholangitis, Ulcerative colitis",

author = "{N{\'u}{\~n}ez F.}, Paulina and {Quera P.}, Rodrigo and Fernando Gomoll{\'o}n",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Espa{\~n}a, S.L.U.",

year = "2019",

month = may,

doi = "10.1016/j.gastrohep.2019.02.004",

language = "Spanish",

volume = "42",

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TY - JOUR

T1 - Colangitis esclerosante primaria y enfermedad inflamatoria intestinal

T2 - interrelación intestino-hígado

AU - Núñez F., Paulina

AU - Quera P., Rodrigo

AU - Gomollón, Fernando

PY - 2019/5

Y1 - 2019/5

N2 - The association between inflammatory bowel disease (IBD)and primary sclerosing cholangitis should be considered a distinct clinical entity. This association involves genetic abnormalities, epidemiological factors (more common in men, with no a geographical pattern)and, commonly, subclinical inflammation, predominance of the right colon (endoscopic and histological), backwash ileitis and rectal sparing. Furthermore, there is an increased risk of colorectal cancer and cholangiocarcinoma. The aim of this review is to show how IBD influences the progression of this entity, transplantation requirements and recurrence. We also discuss the current evidence on the use of biological therapy in this group of patients.

AB - The association between inflammatory bowel disease (IBD)and primary sclerosing cholangitis should be considered a distinct clinical entity. This association involves genetic abnormalities, epidemiological factors (more common in men, with no a geographical pattern)and, commonly, subclinical inflammation, predominance of the right colon (endoscopic and histological), backwash ileitis and rectal sparing. Furthermore, there is an increased risk of colorectal cancer and cholangiocarcinoma. The aim of this review is to show how IBD influences the progression of this entity, transplantation requirements and recurrence. We also discuss the current evidence on the use of biological therapy in this group of patients.

KW - Crohn's disease

KW - Inflammatory bowel disease

KW - Primary sclerosing cholangitis

KW - Ulcerative colitis

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U2 - 10.1016/j.gastrohep.2019.02.004

DO - 10.1016/j.gastrohep.2019.02.004

M3 - Review article

C2 - 30948141

AN - SCOPUS:85063618398

SN - 0210-5705

VL - 42

SP - 316

EP - 325

JO - Gastroenterologia y Hepatologia

JF - Gastroenterologia y Hepatologia

IS - 5

ER -

Colangitis esclerosante primaria y enfermedad inflamatoria intestinal: interrelación intestino-hígado

Resumen

Nota bibliográfica

Palabras clave

ODS de las Naciones Unidas

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