Cardiotoxicidad inducida por tratamientos oncológicos. Fundamentos para la implementación de equipos de Cardio-Oncología

René Hameau, Luigi Gabrielli, Marcelo Garrido, Ana María Guzmán, Ignacio Retamal, María José Vacarezza, Douglas Greig, Mauricio Ocqueteau, César Sánchez, Marcela Pizarro, Alejandro Corvalán, Sergio Lavandero, Pablo F. Castro, Gonzalo Martínez*

*Autor correspondiente de este trabajo

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)

Resumen

Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, these new therapies, along with greater patient survival, are associated with an increase in untoward effects, particularly in the cardiovascular system. Although cardiotoxicity induced by oncologic treatments affects predominantly the myocardium, it can also involve other structures of the cardiovascular system, becoming one of the main causes of morbidity and mortality in those who survive cancer. The main objective of cardio-oncology is to achieve the maximum benefits of oncologic treatments while minimizing their deleterious cardiovascular effects. It harbors the stratification of patients at risk of cardiotoxicity, the implementation of diagnostic tools (imaging techniques and biomarkers) for early diagnosis, preventive strategies and early treatment options for the complications. Herein, we discuss the basic knowledge for the implementation of cardio-oncology units and their role in the management of cancer patients, the diagnostic tools available to detect cardiotoxicity and the present therapeutic options.

Título traducido de la contribuciónCardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units
Idioma originalEspañol
Páginas (desde-hasta)68-77
Número de páginas10
PublicaciónRevista Medica de Chile
Volumen146
N.º1
DOI
EstadoPublicada - ene. 2018
Publicado de forma externa

Nota bibliográfica

Publisher Copyright:
© 2018, Sociedad Medica de Santiago. All rights reserved.

Palabras clave

  • Cancer
  • Cardiotoxicity
  • Drug therapy
  • Heart failure
  • Radiotherapy

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