Cambios del estado clínico periodontal según consumo sistémico de estatinas

David Rosenberg; Catherine Andrade; Ricardo E. Larrea; Alejandra Chaparro; c silva; Valeria Ramírez; Cinthya Urquidi Bellota; Deborah Violant; José Nart

doi:10.1016/j.piro.2015.03.005

Cambios del estado clínico periodontal según consumo sistémico de estatinas

David Rosenberg^*, Catherine Andrade, Ricardo E. Larrea, Alejandra Chaparro, c silva, Valeria Ramírez, Cinthya Urquidi Bellota, Deborah Violant, José Nart

^*Autor correspondiente de este trabajo

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

Resumen

Objetivos
Describir los cambios del estado clínico periodontal de pacientes según el consumo sistémico de estatinas por indicación del cardiólogo.
Material y método
Se realizó un estudio descriptivo en el cual se reclutaron pacientes con periodontitis crónica derivados desde cardiología de la Clínica Dávila. Un grupo de ellos iniciaría terapia de estatinas. Se realizaron mediciones clínicas periodontales de profundidad al sondaje (PS), nivel de inserción clínico, índice de sangrado, área de superficie periodontal inflamada, e índice gingival, al inicio (antes de comenzar la terapia de estatinas) y 6 meses después. Los datos fueron analizados utilizando estadística descriptiva.
Resultados
Diez pacientes participaron del estudio, 5 con indicación de estatinas. El grupo con estatinas en comparación con el grupo sin estatinas presentó una disminución en promedio: de PS (0,4 mm versus 0,13 mm); porcentaje de sitios con PS ≥ 5 mm (4,16% versus 1,09%); de nivel de inserción clínico (0,5 mm versus 0,2 mm), índice de sangrado (27,16% versus 8,8%) y área de superficie periodontal inflamada (305,68 mm2 versus 121,35).
Conclusiones
Estos resultados sugieren que pacientes con periodontitis crónica podrían obtener beneficios de la terapia sistémica con estatinas. Se requiere de estudios clínicos con asignación aleatoria y el óptimo tamaño muestral que comprueben el efecto e impacto de las estatinas sobre el estado periodontal.

Título traducido de la contribución	Changes in clinic periodontal status according to systemic statins intake
Idioma original	Español
Páginas (desde-hasta)	111-116
Publicación	Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral
Volumen	8
N.º	2
Fecha en línea anticipada	13 may. 2015
DOI	https://doi.org/10.1016/j.piro.2015.03.005
Estado	Publicada - 15 ago. 2015

Nota bibliográfica

Palabras clave

Periodontitis
Estatinas
Cardiología

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10.1016/j.piro.2015.03.005

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@article{028d175c705248dcbb3834170f41359e,

title = "Cambios del estado cl{\'i}nico periodontal seg{\'u}n consumo sist{\'e}mico de estatinas",

abstract = "ObjectiveTo describe changes in periodontal clinical status of patients according to systemic statin use prescribed by a cardiologist.Material and methodsA descriptive study was performed on patients with chronic periodontitis referred from the Department of Cardiovascular Diseases of D{\'a}vila Clinic. A group of them began statin therapy. Clinical measurements of periodontal probing depth (PD), clinical attachment level, bleeding index, periodontal inflamed surface area, and gingival index, were performed at baseline (before starting statin therapy) and 6 months later. Data were analyzed using descriptive statistics.ResultsA total of 10 patients participated in the study, and five of them received statin therapy. The statin group compared to the group without statins, showed a mean decrease in: PD (0.4 mm versus 0.13 mm); percentage of PS sites ≥ 5 mm (4.16% versus 1.09%); clinical attachment level (0.5 mm versus 0.2 mm), bleeding index (27.16% versus 8.8%), and periodontal inflamed surface area (305.68 versus 121.35 mm2).ConclusionsThese results suggest that patients with chronic periodontitis may benefit from systemic therapy with statins. Randomized clinical trials with optimal sample size are required to check the effect and impact of statins on the periodontal status.",

keywords = "Periodontitis, Estatinas, Cardiolog{\'i}a, Periodontitis, Statins, Cardiology",

author = "David Rosenberg and Catherine Andrade and Larrea, {Ricardo E.} and Alejandra Chaparro and c silva and Valeria Ram{\'i}rez and {Urquidi Bellota}, Cinthya and Deborah Violant and Jos{\'e} Nart",

note = "Copyright {\textcopyright} 2014 Sociedad de Periodoncia de Chile, Sociedad de Implantolog{\'i}a Oral de Chile y Sociedad de Pr{\'o}tesis y Rehabilitaci{\'o}n Oral de Chile. Published by Elsevier Espa{\~n}a S.L.",

year = "2015",

month = aug,

day = "15",

doi = "10.1016/j.piro.2015.03.005",

language = "Spanish",

volume = "8",

pages = "111--116",

journal = "Revista Cl{\'i}nica de Periodoncia, Implantolog{\'i}a y Rehabilitaci{\'o}n Oral",

issn = "0719-0107",

number = "2",

}

TY - JOUR

T1 - Cambios del estado clínico periodontal según consumo sistémico de estatinas

AU - Rosenberg, David

AU - Andrade, Catherine

AU - Larrea, Ricardo E.

AU - Chaparro, Alejandra

AU - silva, c

AU - Ramírez, Valeria

AU - Urquidi Bellota, Cinthya

AU - Violant, Deborah

AU - Nart, José

PY - 2015/8/15

Y1 - 2015/8/15

N2 - ObjectiveTo describe changes in periodontal clinical status of patients according to systemic statin use prescribed by a cardiologist.Material and methodsA descriptive study was performed on patients with chronic periodontitis referred from the Department of Cardiovascular Diseases of Dávila Clinic. A group of them began statin therapy. Clinical measurements of periodontal probing depth (PD), clinical attachment level, bleeding index, periodontal inflamed surface area, and gingival index, were performed at baseline (before starting statin therapy) and 6 months later. Data were analyzed using descriptive statistics.ResultsA total of 10 patients participated in the study, and five of them received statin therapy. The statin group compared to the group without statins, showed a mean decrease in: PD (0.4 mm versus 0.13 mm); percentage of PS sites ≥ 5 mm (4.16% versus 1.09%); clinical attachment level (0.5 mm versus 0.2 mm), bleeding index (27.16% versus 8.8%), and periodontal inflamed surface area (305.68 versus 121.35 mm2).ConclusionsThese results suggest that patients with chronic periodontitis may benefit from systemic therapy with statins. Randomized clinical trials with optimal sample size are required to check the effect and impact of statins on the periodontal status.

AB - ObjectiveTo describe changes in periodontal clinical status of patients according to systemic statin use prescribed by a cardiologist.Material and methodsA descriptive study was performed on patients with chronic periodontitis referred from the Department of Cardiovascular Diseases of Dávila Clinic. A group of them began statin therapy. Clinical measurements of periodontal probing depth (PD), clinical attachment level, bleeding index, periodontal inflamed surface area, and gingival index, were performed at baseline (before starting statin therapy) and 6 months later. Data were analyzed using descriptive statistics.ResultsA total of 10 patients participated in the study, and five of them received statin therapy. The statin group compared to the group without statins, showed a mean decrease in: PD (0.4 mm versus 0.13 mm); percentage of PS sites ≥ 5 mm (4.16% versus 1.09%); clinical attachment level (0.5 mm versus 0.2 mm), bleeding index (27.16% versus 8.8%), and periodontal inflamed surface area (305.68 versus 121.35 mm2).ConclusionsThese results suggest that patients with chronic periodontitis may benefit from systemic therapy with statins. Randomized clinical trials with optimal sample size are required to check the effect and impact of statins on the periodontal status.

KW - Periodontitis

KW - Estatinas

KW - Cardiología

KW - Periodontitis

KW - Statins

KW - Cardiology

U2 - 10.1016/j.piro.2015.03.005

DO - 10.1016/j.piro.2015.03.005

M3 - Article

SN - 0719-0107

VL - 8

SP - 111

EP - 116

JO - Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral

JF - Revista Clínica de Periodoncia, Implantología y Rehabilitación Oral

IS - 2

ER -

Cambios del estado clínico periodontal según consumo sistémico de estatinas

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