Tumores Neuroendocrinos: Un desafío transversal

Diego Carrillo; Matías Muñoz Medel; Ignacio Retamal; Mauricio Pinto; María L. Bravo; Bruno Nervi; José Peña; Yasna Valenzuela; Francisco J. Guarda; Flavia Nilo; Fernando Bello; Pilar Orellana; Daniel Vicentini; Juan Carlos Quintana; Paula J.  Torres; José Luis Leal; Marcelo Garrido

doi:10.4067/S0034-98872021000600888

Tumores Neuroendocrinos: Un desafío transversal

Translated title of the contribution: Update on neuroendocrine tumors

Diego Carrillo, Matías Muñoz Medel, Ignacio Retamal, Mauricio Pinto, María L. Bravo, Bruno Nervi, José Peña, Yasna Valenzuela, Francisco J. Guarda, Flavia Nilo, Fernando Bello, Pilar Orellana, Daniel Vicentini, Juan Carlos Quintana, Paula J. Torres, José Luis Leal, Marcelo Garrido^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Neuroendocrine Tumors (NETs) encompass a wide variety of tumors arising from neuroendocrine cells, which produce bioactive substances. The incidence of NETs increased significantly lately, becoming one of the most common tumors of the digestive tract. Their clinical presentation is as diverse as their capacity for hormone production. Carcinoid syndrome is the most common hormonal syndrome produced by NETs and is characterized by diarrhea, flushing and cardiac valvular lesions. New research brought multiple changes in the classification of these neoplasms and a new understanding about their diagnosis and treatment, promoting a multidisciplinary approach. Somatostatin analogues, radiation, biological, and cytotoxic drugs have improved the prognosis of these patients, which entails a great challenge for healthcare providers.

Translated title of the contribution	Update on neuroendocrine tumors
Original language	Spanish
Pages (from-to)	888-898
Number of pages	11
Journal	Revista Medica de Chile
Volume	149
Issue number	6
DOIs	https://doi.org/10.4067/S0034-98872021000600888
State	Published - Jun 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 Sociedad Medica de Santiago. All rights reserved.

Keywords

Biomarkers
Tumor
Malignant Carcinoid Syndrome
Neuroendocrine Tumors
Somatostatin

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4067/S0034-98872021000600888License: CC BY

Cite this

Carrillo, D., Muñoz Medel, M., Retamal, I., Pinto, M., Bravo, M. L., Nervi, B., Peña, J., Valenzuela, Y., Guarda, F. J., Nilo, F., Bello, F., Orellana, P., Vicentini, D., Quintana, J. C., Torres, P. J., Leal, J. L., & Garrido, M. (2021). Tumores Neuroendocrinos: Un desafío transversal. Revista Medica de Chile, 149(6), 888-898. https://doi.org/10.4067/S0034-98872021000600888

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abstract = "Neuroendocrine Tumors (NETs) encompass a wide variety of tumors arising from neuroendocrine cells, which produce bioactive substances. The incidence of NETs increased significantly lately, becoming one of the most common tumors of the digestive tract. Their clinical presentation is as diverse as their capacity for hormone production. Carcinoid syndrome is the most common hormonal syndrome produced by NETs and is characterized by diarrhea, flushing and cardiac valvular lesions. New research brought multiple changes in the classification of these neoplasms and a new understanding about their diagnosis and treatment, promoting a multidisciplinary approach. Somatostatin analogues, radiation, biological, and cytotoxic drugs have improved the prognosis of these patients, which entails a great challenge for healthcare providers.",

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author = "Diego Carrillo and {Mu{\~n}oz Medel}, Mat{\'i}as and Ignacio Retamal and Mauricio Pinto and Bravo, {Mar{\'i}a L.} and Bruno Nervi and Jos{\'e} Pe{\~n}a and Yasna Valenzuela and Guarda, {Francisco J.} and Flavia Nilo and Fernando Bello and Pilar Orellana and Daniel Vicentini and Quintana, {Juan Carlos} and Torres, {Paula J.} and Leal, {Jos{\'e} Luis} and Marcelo Garrido",

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AU - Muñoz Medel, Matías

AU - Retamal, Ignacio

AU - Pinto, Mauricio

AU - Bravo, María L.

AU - Nervi, Bruno

AU - Peña, José

AU - Valenzuela, Yasna

AU - Guarda, Francisco J.

AU - Nilo, Flavia

AU - Bello, Fernando

AU - Orellana, Pilar

AU - Vicentini, Daniel

AU - Quintana, Juan Carlos

AU - Torres, Paula J.

AU - Leal, José Luis

AU - Garrido, Marcelo

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AB - Neuroendocrine Tumors (NETs) encompass a wide variety of tumors arising from neuroendocrine cells, which produce bioactive substances. The incidence of NETs increased significantly lately, becoming one of the most common tumors of the digestive tract. Their clinical presentation is as diverse as their capacity for hormone production. Carcinoid syndrome is the most common hormonal syndrome produced by NETs and is characterized by diarrhea, flushing and cardiac valvular lesions. New research brought multiple changes in the classification of these neoplasms and a new understanding about their diagnosis and treatment, promoting a multidisciplinary approach. Somatostatin analogues, radiation, biological, and cytotoxic drugs have improved the prognosis of these patients, which entails a great challenge for healthcare providers.

KW - Biomarkers

KW - Tumor

KW - Malignant Carcinoid Syndrome

KW - Neuroendocrine Tumors

KW - Somatostatin

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DO - 10.4067/S0034-98872021000600888

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VL - 149

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EP - 898

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JF - Revista Medica de Chile

IS - 6

ER -

Tumores Neuroendocrinos: Un desafío transversal

Abstract

Bibliographical note

Keywords

UN SDGs

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