TY - JOUR
T1 - Trastorno depresivo mayor en pacientes con acné
AU - Hasbún Zegpi, M. Trinidad
AU - Navarrete, Andres
AU - Herrada, Luis
AU - Valenzuela, Andrés
AU - Bustamante, Francisco
AU - Orlandi, Cecilia
PY - 2008/2/1
Y1 - 2008/2/1
N2 - BACKGROUND AND OBJECTIVES: Major depressive disorder is one of the most common psychiatric disorders in patients with acne. The objective was to assess the association between acne and depression. METHOD: We performed a case-control study in a private outpatient clinic in Santiago, Chile. The case group was composed of adult patients attending our center with a clinical diagnosis of acne, established by an experienced dermatologist. The control group consisted of adult patients without acne who were related to subjects in the case group. Cases and controls were matched by sex, age and socioeconomic status. To measure depressive disorder, the Compound International Diagnostic Interview (CIDI) was applied to both groups. All the numerical variables were compared with Student's t-test and categorical variables were compared with the χ2 test and odds ratios. RESULTS: Sixty patients were included (30 in each group): 21 females and nine males. All patients completed the questionnaire. No significant differences were found between the two groups in any of the demographic variables analyzed. In the case group, nine patients (30%) met the diagnostic criteria for major depressive disorder, whereas only two patients (6.6%) in the control group met these criteria (OR = 6; 95% confidence interval, 1.03-45.22; p = 0.02). CONCLUSIONS: We found a statistically significant association between major depressive disorder and acne. The risk of depression was approximately 6 times greater in patients with this disorder.
AB - BACKGROUND AND OBJECTIVES: Major depressive disorder is one of the most common psychiatric disorders in patients with acne. The objective was to assess the association between acne and depression. METHOD: We performed a case-control study in a private outpatient clinic in Santiago, Chile. The case group was composed of adult patients attending our center with a clinical diagnosis of acne, established by an experienced dermatologist. The control group consisted of adult patients without acne who were related to subjects in the case group. Cases and controls were matched by sex, age and socioeconomic status. To measure depressive disorder, the Compound International Diagnostic Interview (CIDI) was applied to both groups. All the numerical variables were compared with Student's t-test and categorical variables were compared with the χ2 test and odds ratios. RESULTS: Sixty patients were included (30 in each group): 21 females and nine males. All patients completed the questionnaire. No significant differences were found between the two groups in any of the demographic variables analyzed. In the case group, nine patients (30%) met the diagnostic criteria for major depressive disorder, whereas only two patients (6.6%) in the control group met these criteria (OR = 6; 95% confidence interval, 1.03-45.22; p = 0.02). CONCLUSIONS: We found a statistically significant association between major depressive disorder and acne. The risk of depression was approximately 6 times greater in patients with this disorder.
KW - Acne
KW - Case
KW - Control
KW - Major depressive disorder
UR - http://www.scopus.com/inward/record.url?scp=40549128317&partnerID=8YFLogxK
U2 - 10.1016/S0213-9251(08)70980-8
DO - 10.1016/S0213-9251(08)70980-8
M3 - Article
AN - SCOPUS:40549128317
SN - 0213-9251
VL - 23
SP - 52
EP - 54
JO - Piel
JF - Piel
IS - 2
ER -