Clostridium diffcile (CD) infection is increasing in frequency and severity in in-hospital and outpatient clinical settings, with a recurrence that can reach 30% after frst episode. The recurrences are usually treated with longer courses of metronidazole or vancomycin. Other treatments have been used, such as probiotics, fdaxomicin, rifaxi-min, immunoglobulins and monoclonal antibodies against toxins A and B. Fecal microbiota transplantation (FMT) has emerged as a promising strategy in this group of patients, with effectiveness greater than 90%. We present the frst case reported in Chile of this therapeutic strategy in a patient with Crohn´s disease and recurrent CD infection who presented after the fecal transplantation an Escherichia coli bacteremia, suggesting the need for caution in the use of this strategy. 10 months after the FMT the patient presented a new episode of E. coli bacteremia and two episodes of diarrhea due to CD infection, treated both of them with vancomycin with good clinical response.
|Translated title of the contribution||Fecal microbiota transplantation: First case report in Chile and review|
|Number of pages||6|
|Journal||Revista Chilena de Infectologia|
|State||Published - 1 Aug 2014|
Bibliographical notePublisher Copyright:
© 2014, Sociedad Chilena de Infectologia. All rights reserved.