Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada

Translated title of the contribution: Fecal microbiota transplantation in an older patient with Clostridioides difficile recurrent infection. Report of one case

Paulina Núñez, Rodrigo Quera*, Christian von Muhlenbrock, Alexandra Concha, Katherine Flores

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Clostridioides difficile infection (CDI) is a major public health problem and responsible for significant morbidity and mortality. Eighty percent of CDIs occur in adults older than 65 years of age due to a decreased gastrointestinal microbial diversity, immunosenescence and frailty. Thus, the most reported risk factor for recurrent CDI is older age since nearly 60% of cases occur in individuals aged ≥ 65 years. Fecal microbiota transplantation (FMT) is a highly cost-effective alternative to antibiotic treatment for patients with recurrent CDI. We report a 75-year-old male with recurrent CDI, who received a FMT after several unsuccessful antimicrobial treatments. He had a satisfactory evolution after the procedure and remained without diarrhea during the ensuing five months.

Translated title of the contributionFecal microbiota transplantation in an older patient with Clostridioides difficile recurrent infection. Report of one case
Original languageSpanish
Pages (from-to)1396-1400
Number of pages5
JournalRevista Medica de Chile
Volume150
Issue number10
DOIs
StatePublished - Oct 2022

Bibliographical note

Publisher Copyright:
© 2022 Sociedad Medica de Santiago. All rights reserved.

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