Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada

Translated title of the contribution: Fecal microbiota transplantation in an older patient with Clostridioides difficile recurrent infection: report of one case

Paulina Núñez, Rodrigo Quera*, Christian von Muhlenbrock, Alexandra Concha, Katherine Flores

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Clostridioides difficile infection (CDI) is a major public health problem and responsible for significant morbidity and mortality. Eighty percent of CDIs occur in adults older than 65 years of age due to a decreased gastrointestinal microbial diversity, immunosenescence and frailty. Thus, the most reported risk factor for recurrent CDI is older age since nearly 60% of cases occur in individuals aged ≥ 65 years. Fecal microbiota transplantation (FMT) is a highly cost-effective alternative to antibiotic treatment for patients with recurrent CDI. We report a 75-year-old male with recurrent CDI, who received a FMT after several unsuccessful antimicrobial treatments. He had a satisfactory evolution after the procedure and remained without diarrhea during the ensuing five months.

Translated title of the contributionFecal microbiota transplantation in an older patient with Clostridioides difficile recurrent infection: report of one case
Original languageSpanish
Pages (from-to)1396-1400
Number of pages5
JournalRevista Medica de Chile
Volume150
Issue number10
DOIs
StatePublished - Oct 2022

Bibliographical note

Publisher Copyright:
© 2022 Sociedad Medica de Santiago. All rights reserved.

Keywords

  • aged
  • Clostridioidesdifficile
  • Fecal Microbiota Transplantation
  • Fidaxomicin
  • Recurrence

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