The use of topical treatment and middle-inner ear interaction

Marcos V. Goycoolea*, Leandro Rodríguez, Pilar Epprecht

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Ototoxicity secondary to the use of ear drops involves the concept that under specific circumstances, some of the components of these preparations can reach the inner ear and cause sensory damage. This chapter is a review of the potential routes of passage of these components to the inner ear, the pathogenesis of these events, and the experimental and clinical evidence available. Based on these descriptions and observations, safer means of using drops are suggested.

Original languageEnglish
Title of host publicationTextbook of Otitis Media
Subtitle of host publicationThe Basics and Beyond
PublisherSpringer International Publishing
Pages275-278
Number of pages4
ISBN (Electronic)9783031409493
ISBN (Print)9783031409486
DOIs
StatePublished - 29 Dec 2023

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2023. All rights reserved.

Keywords

  • Ototoxicity and ototopical medications
  • Ototoxicity of ear drops
  • Round window membrane permeability
  • Routes from middle to inner ear
  • Use of ear drops

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