Susceptibilidad de Cepas de Candida Oral a Extracto Etanólico del Propóleo Chileno de Olmué

Translated title of the contribution: Susceptibility of Oral Candida Strains to Ethanol Extract of Chilean Propolis of Olmué

Natalia Maureira, Paulina Viera, Alejandra Fernandez, Madelein Urrejola, Cristian Bravo, Francisca Mardones, Enrique D. Vines, Ziyad S. Haidar

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ABSTRACT: Fungal (or yeast) infections; mycoses, occurring in the oral mucous membranes, of Candida species (mostly C. albicans, a normal component of the oral microbiota), also known as oral thrush or oral candidiasis (OC), can be diagnosed via the recognition of clinical changes and the presence of pseudohyphae, hyphae or yeasts in samples obtained by exfoliative cytology and/or biopsy. Topical pharmacological preparations and drugs such as Nystatin and Miconazole are used in the treatment of CO. However, there are forms of Candida with resistance to such conventional treatment approaches. Therefore, the aim of this study is to determine the in vitro susceptibility of Candida spp.; an ethanolic extract of propolis from Olmué. Hence, an experimental in vitro descriptive study was carried out in which the effect of an ethanolic extract of propolis used as antifungal on strains of Candida spp. obtained from the oral cavity (palatine mucosa) of 31 individuals, diagnosed with OC (subdenture stomatitis) is determined. Natural propolis was obtained from the Olmué area, in the 5th region of Chile. It was found that 100 % of the samples with propolis concentration ranging from 0.1 mg / mL to 1.6 mg / mL presented a degree of inhibition in the growth of OC. On the other hand, the ethanolic extract of propolis that generated inhibition in the largestnumber of samples was 0.4 mg / mL (41.94 % of the samples) followed by the concentration of 0.2 mg / mL (35 % of the samples). Therefore, it can be concluded that the ethanolic extract of Chilean propolis obtained from the Olmué area has the ability to inhibit the growth of Candida spp. in vitro in a dosage-dependent manner.
Translated title of the contributionSusceptibility of Oral Candida Strains to Ethanol Extract of Chilean Propolis of Olmué
Original languageSpanish
Pages (from-to)295-303
JournalInternational journal of odontostomatology
Issue number3
StatePublished - 13 Nov 2017


  • propolis
  • Candida albicans
  • oral cavity.


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