PADRONIZAÇÃO E UTILIDADE DIAGNÓSTICA DO FRONTAL BATERIA DE AVALIAÇÃO PARA PESSOAS SAUDÁVEIS E PACIENTES COM DEMÊNCIA NA POPULAÇÃO CHILENA

Translated title of the contribution: Standardization and diagnostic utility of the Frontal Assessment Battery for healthy people and patients with dementia in the Chilean population

Fabrissio Grandi, David Martínez-Pernía, Mario Parra, Loreto Olavarria, David Huepe, Patricia Alegria, Álvaro Aliaga, Patricia Lillo, Carolina Delgado, Marcela Tenorio, Ricardo Rosas, Oscar López, James Becker, Andrea Slachevsky*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The Frontal Assessment Battery (FAB) is a screening test that measures executive functions. Although this instrument has been validated in several countries, its diagnostic utility in a Chilean population has not been studied yet. Objectives: This study aimed to (1) adapt FAB in a Chilean population; (2) study the psychometric properties of the FAB in a Chilean population; (3) assess the sociodemographic influence in the performance of the FAB in a sample of healthy controls (HC); and (4) develop normative data for this healthy group. Methods: A HC (n=344) and a group of patients with dementia (n=156) were assessed with the Chilean version of FAB. Results: FAB showed good internal consistency (Cronbach’s alpha=0.79) and acceptable validity based on the relationship with other variables. Factor analysis showed the unidimensionality of the instrument. Significant differences were found in the total FAB value between the HC and dementia groups. With the matched sample, the established cutoff point was 13.5, showing a sensitivity of 80.8% and a specificity of 90.4%. Regression analysis showed that education and age significantly predicted FAB performance in the healthy group. Finally, normative data are provided. Conclusions: This study shows that FAB is a useful tool to discriminate between healthy people and people with dementia. However, further studies are needed to explore the capacity of the instrument to characterize the dysexecutive syndrome in people with dementia in the Chilean population.

Translated title of the contributionStandardization and diagnostic utility of the Frontal Assessment Battery for healthy people and patients with dementia in the Chilean population
Original languagePortuguese
Pages (from-to)69-78
Number of pages10
JournalDementia e Neuropsychologia
Volume16
Issue number1
DOIs
StatePublished - 1 Jan 2022

Bibliographical note

Funding Information:
Funding: ANID/FONDAP/15150012; ANID/FONDEF/ID18I10113; ANID/Fondecyt/1191726, 1210176, and 1210195 and MULTI-PARTNER CONSORTIUM TO EXPAND DEMENTIA RESEARCH IN LATIN AMERICA [ReDLat, supported by the National Institutes of Health, National Institutes of Aging (P30 AG066468),Alzheimer’s Association (SG-20-725707), Tau Consortium, and Global Brain Health Institute] and Alzheimer’s Association GBHI ALZ UK-20-639295.

Funding Information:
ANID/FONDAP/15150012; ANID/FONDEF/ID18I10113; ANID/Fondecyt/1191726, 1210176, and 1210195 and MULTI-PARTNER CONSORTIUM TO EXPAND DEMENTIA RESEARCH IN LATIN AMERICA [ReDLat, supported by the National Institutes of Health, National Institutes of Aging (P30 AG066468), Alzheimer?s Association (SG-20-725707), Tau Consortium, and Global Brain Health Institute] and Alzheimer?s Association GBHI ALZ UK-20-639295. Study data were partially collected and managed using RedCap electronic data capture tools hosted at Faculty of Medicine, University of Chile, GERO, Memory and Neuropsychiatry Clinic, Faculty of Medicine Hospital del Salvador, University of Chile, and German Clinic.

Publisher Copyright:
© 2022, Associacao Arquivos de Neuro-Psiquiatria. All rights reserved.

Keywords

  • Dementia
  • Executive Function
  • Mental Status and Dementia Tests
  • Neurodegenerative Diseases

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