Simultaneous sinus floor elevation and implant placement using leukocyte- and platelet-rich fibrin as a sole graft material

Bo Molemans*, Simone Cortellini, Reinhilde Jacobs, Wim Teughels, Nelson Pinto, Marc Quirynen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Purpose: Sinus floor elevation (SFE) and simultaneous implant placement is predictable and reproducible. However, the graft material for the antral cavity remains a topic of debate. Considering the high osteogenic potential of the sinus membrane, most graft materials are generally accepted. This study aimed to assess the outcome of simultaneous SFE and implant placement, using leukocyte- and platelet-rich fibrin (L-PRF) as a sole graft material. Materials and Methods: This study was designed as a single cohort prospective study. Clinical and radiographic measurements (cone beam computed tomography [CBCT]) were performed immediately after implant placement and at abutment connection (6 months later). The amount of newly formed bone was linearly recorded on cross-sectional images. Four measurements (mesial, distal, buccal, palatal) were registered with the axis of the implant as reference. Results: Six lateral and 22 transalveolar SFEs were performed in 26 patients with simultaneous implant placement. Six months after surgery, 27/29 implants were clinically integrated. The mean vertical bone gain was 3.4 ± 1.2 mm and 5.4 ± 1.5 mm for transalveolar SFE and lateral SFE, respectively. The level of the new sinus floor was in all cases in continuation with the apex of the implant, and the peri-implant crestal bone height was stable. Conclusion: L-PRF as a sole graft material during simultaneous SFE and implant placement proved to be a practical, safe, and economical subsinus graft material, resulting in natural bone formation.

Original languageEnglish
Pages (from-to)1195-1201
Number of pages7
JournalInternational Journal of Oral and Maxillofacial Implants
Issue number5
StatePublished - 2019
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2019 by Quintessence Publishing Co Inc.


  • Bioactive growth factors
  • Bone graft
  • Bone substitute
  • Leucocyte and platelet rich fibrin
  • Sinus lift
  • Surgery


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