Sex-Differences in the Oxygenation Levels of Intercostal and Vastus Lateralis Muscles During Incremental Exercise

Maximiliano Espinosa-Ramírez, Eduardo Moya-Gallardo, Felipe Araya-Román, Santiago Riquelme-Sánchez, Guido Rodriguez-García, W. Darlene Reid, Ginés Viscor, Oscar F. Araneda, Luigi Gabrielli, Felipe Contreras-Briceño*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

This study aimed to examine sex differences in oxygen saturation in respiratory (SmO2-m.intercostales) and locomotor muscles (SmO2-m.vastus lateralis) while performing physical exercise. Twenty-five (12 women) healthy and physically active participants were evaluated during an incremental test with a cycle ergometer, while ventilatory variables [lung ventilation ((Formula presented.) E), tidal volume (Vt), and respiratory rate (RR)] were acquired through the breath-by-breath method. SmO2 was acquired using the MOXY® devices on the m.intercostales and m.vastus lateralis. A two-way ANOVA (sex × time) indicated that women showed a greater significant decrease of SmO2-m.intercostales, and men showed a greater significant decrease of SmO2-m.vastus lateralis. Additionally, women reached a higher level of ΔSmO2-m.intercostales normalized to (Formula presented.) E (L⋅min–1) (p < 0.001), whereas men had a higher level of ΔSmO2-m.vastus lateralis normalized to peak workload-to-weight (watts⋅kg–1, PtW) (p = 0.049), as confirmed by Student’s t-test. During an incremental physical exercise, women experienced a greater cost of breathing, reflected by greater deoxygenation of the respiratory muscles, whereas men had a higher peripheral load, indicated by greater deoxygenation of the locomotor muscles.

Original languageEnglish
Article number738063
Pages (from-to)738063
JournalFrontiers in Physiology
Volume12
DOIs
StatePublished - 1 Oct 2021

Bibliographical note

Publisher Copyright:
© Copyright © 2021 Espinosa-Ramírez, Moya-Gallardo, Araya-Román, Riquelme-Sánchez, Rodriguez-García, Reid, Viscor, Araneda, Gabrielli and Contreras-Briceño.

Keywords

  • cost of breathing
  • exercise
  • near-infrared spectroscopy
  • respiratory muscles
  • sex

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