Selection of process alternatives for lignocellulosic bioethanol production using a MILP approach

Felipe Scott, Fabrizio Venturini, Germán Aroca, Raúl Conejeros*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


This work proposes a decision-making framework for the selection of processes and unit operations for lignocellulosic bioethanol production. Process alternatives are described by its capital and operating expenditures, its contribution to process yield and technological availability information. A case study in second generation ethanol production using Eucalyptus globulus as raw material is presented to test the developed process synthesis tool. Results indicate that production cost does not necessarily decrease when yield increases. Hence, optimal processes can be found at the inflexion point of total costs and yield. The developed process synthesis tool provides results with an affordable computational cost, existing optimization tools and an easy-to-upgrade description of the process alternatives. These features made this tool suitable for process screening when incomplete information regarding process alternatives is available.

Original languageEnglish
Pages (from-to)525-534
Number of pages10
JournalBioresource Technology
StatePublished - Nov 2013
Externally publishedYes

Bibliographical note

Funding Information:
Financial support granted to F. Scott by CONICYT’s scholarship program (Comisión Nacional de Investigación Científica y Tecnológica) is gratefully acknowledged. This work was funded by Innova Chile Project 208-7320 Technological Consortium Bioenercel S.A.


  • Biofuels
  • LEPC
  • MILP
  • MILP optimization
  • MINLP optimization
  • Process synthesis
  • SSCF
  • SSF
  • Second generation bioethanol


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