Risk factors for permanent kidney damage in children with urinary tract infection

Pilar Orellana, Felipe Cavagnaro, Paulina Baquedano, Edda Lagomarsino, Cristián García, Luis Villarroel, Juan Eduardo Carreño, Luis Meneses

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

BACKGROUND: In children, urinary tract infection (UTI) is a very common disease, and can cause permanent kidney damage. AIM: To determine risk factors for permanent kidney damage, in children with UTI. PATIENTS AND METHODS: In 337 children with UTI (237 female, mean age 4.2 years) a static renal scintigraphy was performed to assess the presence of permanent kidney damage. The history of vesicoureteral reflux and number of episodes of UTI was obtained. RESULTS: One hundred three children had a history of one episode of infection and the rest had recurrent infections. Permanent kidney damage was observed in 161 children (48%). This damage was observed in 39% of children of less than one year of age, in 43% of children aged 1 to 5 years of age and in 58% of children older than 5 years (p = 0.02). Sixty three percent of 122 children with vesicoureteral reflux had permanent kidney damage, compared with 27% of children without this condition (p < 0.001). Likewise, damage was observed in 36% of children with one episode of infection and 47% of children with recurrent infections (p < 0.01). No gender differences were observed. CONCLUSIONS: Vesicoureteral reflux, recurrence of UTI and age are associated with permanent renal damage in children with UTI.

Translated title of the contributionRisk factors for permanent kidney damage in children with urinary tract infection
Original languageSpanish
Pages (from-to)1147-1153
Number of pages7
JournalRevista Medica de Chile
Volume130
Issue number10
StatePublished - Oct 2002
Externally publishedYes

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