Primer trasplante de intestino en Chile.: Caso clínico

Erwin Buckel G; Mario Ferrario B; Mario Uribe M; Gloria González G; Jorge Godoy L; Fernando Fluxá G; Rodrigo Quera P; Verner Codoceo R; Jorge Morales B; David Benavente M; María Teresa Santander D; Cristina Herzog O

Primer trasplante de intestino en Chile. Caso clínico

Translated title of the contribution: Small bowel transplantation. Report of a single case

Erwin Buckel G^*, Mario Ferrario B, Mario Uribe M, Gloria González G, Jorge Godoy L, Fernando Fluxá G, Rodrigo Quera P, Verner Codoceo R, Jorge Morales B, David Benavente M, María Teresa Santander D, Cristina Herzog O

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Small bowel transplantation is associated with a patient survival at one and five years, of 80% and 63%, respectively. We report a 36 year-old female with short bowel syndrome, subjected to the first small bowel transplantation performed in Chile. A cadaveric graft was used. Immunosuppression was achieved by means of alemtuzumab, tacrolimus, sirolimus, micofenolate mofetil and steroids. Serial endoscopies and biopsies were performed during seven months after transplantation. The most important late complications were a drug induced renal failure, infections caused by opportunistic agents and a gastrointestinal bleeding probably induced by drugs. After 29 months of follow up, the patient is ambulatory, on oral diet only, and with no evidence of graft rejection.

Translated title of the contribution	Small bowel transplantation. Report of a single case
Original language	Spanish
Pages (from-to)	259-263
Number of pages	5
Journal	Revista Medica de Chile
Volume	137
Issue number	2
State	Published - Feb 2009
Externally published	Yes

Keywords

Immunosuppression
Intestine
Small
Transplants

Cite this

@article{3e849209fd5a42fb9806638770498b34,

title = "Primer trasplante de intestino en Chile.: Caso cl{\'i}nico",

abstract = "Small bowel transplantation is associated with a patient survival at one and five years, of 80% and 63%, respectively. We report a 36 year-old female with short bowel syndrome, subjected to the first small bowel transplantation performed in Chile. A cadaveric graft was used. Immunosuppression was achieved by means of alemtuzumab, tacrolimus, sirolimus, micofenolate mofetil and steroids. Serial endoscopies and biopsies were performed during seven months after transplantation. The most important late complications were a drug induced renal failure, infections caused by opportunistic agents and a gastrointestinal bleeding probably induced by drugs. After 29 months of follow up, the patient is ambulatory, on oral diet only, and with no evidence of graft rejection.",

keywords = "Immunosuppression, Intestine, Small, Transplants, Immunosuppression, Intestine, Small, Transplants",

author = "{Buckel G}, Erwin and {Ferrario B}, Mario and {Uribe M}, Mario and {Gonz{\'a}lez G}, Gloria and {Godoy L}, Jorge and {Flux{\'a} G}, Fernando and {Quera P}, Rodrigo and {Codoceo R}, Verner and {Morales B}, Jorge and {Benavente M}, David and {Santander D}, {Mar{\'i}a Teresa} and {Herzog O}, Cristina",

year = "2009",

month = feb,

language = "Spanish",

volume = "137",

pages = "259--263",

journal = "Revista Medica de Chile",

issn = "0034-9887",

publisher = "Sociedad Medica de Santiago",

number = "2",

}

TY - JOUR

T1 - Primer trasplante de intestino en Chile.

T2 - Caso clínico

AU - Buckel G, Erwin

AU - Ferrario B, Mario

AU - Uribe M, Mario

AU - González G, Gloria

AU - Godoy L, Jorge

AU - Fluxá G, Fernando

AU - Quera P, Rodrigo

AU - Codoceo R, Verner

AU - Morales B, Jorge

AU - Benavente M, David

AU - Santander D, María Teresa

AU - Herzog O, Cristina

PY - 2009/2

Y1 - 2009/2

N2 - Small bowel transplantation is associated with a patient survival at one and five years, of 80% and 63%, respectively. We report a 36 year-old female with short bowel syndrome, subjected to the first small bowel transplantation performed in Chile. A cadaveric graft was used. Immunosuppression was achieved by means of alemtuzumab, tacrolimus, sirolimus, micofenolate mofetil and steroids. Serial endoscopies and biopsies were performed during seven months after transplantation. The most important late complications were a drug induced renal failure, infections caused by opportunistic agents and a gastrointestinal bleeding probably induced by drugs. After 29 months of follow up, the patient is ambulatory, on oral diet only, and with no evidence of graft rejection.

AB - Small bowel transplantation is associated with a patient survival at one and five years, of 80% and 63%, respectively. We report a 36 year-old female with short bowel syndrome, subjected to the first small bowel transplantation performed in Chile. A cadaveric graft was used. Immunosuppression was achieved by means of alemtuzumab, tacrolimus, sirolimus, micofenolate mofetil and steroids. Serial endoscopies and biopsies were performed during seven months after transplantation. The most important late complications were a drug induced renal failure, infections caused by opportunistic agents and a gastrointestinal bleeding probably induced by drugs. After 29 months of follow up, the patient is ambulatory, on oral diet only, and with no evidence of graft rejection.

KW - Immunosuppression

KW - Intestine

KW - Small

KW - Transplants

KW - Immunosuppression

KW - Intestine

KW - Small

KW - Transplants

UR - http://www.scopus.com/inward/record.url?scp=67650047259&partnerID=8YFLogxK

M3 - Article

C2 - 19543649

AN - SCOPUS:67650047259

SN - 0034-9887

VL - 137

SP - 259

EP - 263

JO - Revista Medica de Chile

JF - Revista Medica de Chile

IS - 2

ER -

Primer trasplante de intestino en Chile. Caso clínico

Abstract

Keywords

Other files and links

Fingerprint

Cite this