Prevención de enfermedad hemolítica perinatal severa con inmunoglobulina intravenosa en paciente altamente sensibilizada

Catalina Villalobos Andueza; Manuel José Monckeberg Balmaceda; Cristian Kottman González; Juan Carlos Arteaga Rocuant; Enrique Oyarzún Ebensperger

doi:10.4067/S0717-75262021000100076

Prevención de enfermedad hemolítica perinatal severa con inmunoglobulina intravenosa en paciente altamente sensibilizada

Translated title of the contribution: Prevention of severe perinatal hemolytic disease with intravenous immunoglobulin in a highly sensitized patient

Catalina Villalobos Andueza, Manuel José Monckeberg Balmaceda, Cristian Kottman González, Juan Carlos Arteaga Rocuant, Enrique Oyarzún Ebensperger^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Perinatal Hemolytic Disease is uncommon today due to its prevention. However, there are cases of highly sensitized mothers who wish to have a child, that forces this desired pregnancy to be controlled in a special way and be subjected to invasive procedures not exempt from fetal morbidity and mortality. Prenatal use of human inmunoglobulin in the mother may represent a therapeutic alternative. We present a case in which its use prevented the development of intrauterine disease and favored a good neonatal evolution despite the fact that the initial prognosis was very adverse.

Translated title of the contribution	Prevention of severe perinatal hemolytic disease with intravenous immunoglobulin in a highly sensitized patient
Original language	Spanish
Pages (from-to)	76-80
Number of pages	5
Journal	Revista Chilena de Obstetricia y Ginecologia
Volume	86
Issue number	1
DOIs	https://doi.org/10.4067/S0717-75262021000100076
State	Published - Feb 2021

Bibliographical note

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© 2021 Sociedad Chilena de Obstetricia y Ginecologia. All rights reserved.

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10.4067/S0717-75262021000100076

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title = "Prevenci{\'o}n de enfermedad hemol{\'i}tica perinatal severa con inmunoglobulina intravenosa en paciente altamente sensibilizada",

abstract = "Perinatal Hemolytic Disease is uncommon today due to its prevention. However, there are cases of highly sensitized mothers who wish to have a child, that forces this desired pregnancy to be controlled in a special way and be subjected to invasive procedures not exempt from fetal morbidity and mortality. Prenatal use of human inmunoglobulin in the mother may represent a therapeutic alternative. We present a case in which its use prevented the development of intrauterine disease and favored a good neonatal evolution despite the fact that the initial prognosis was very adverse.",

keywords = "Cordocentesis, Immunoglobulin, Intrauterine transfusion, Perinatal hemolytic disease, Rh(D) isoinmmunization",

author = "Andueza, \{Catalina Villalobos\} and Balmaceda, \{Manuel Jos{\'e} Monckeberg\} and Gonz{\'a}lez, \{Cristian Kottman\} and Rocuant, \{Juan Carlos Arteaga\} and Ebensperger, \{Enrique Oyarz{\'u}n\}",

year = "2021",

month = feb,

doi = "10.4067/S0717-75262021000100076",

language = "Spanish",

volume = "86",

pages = "76--80",

journal = "Revista Chilena de Obstetricia y Ginecologia",

issn = "0048-766X",

publisher = "Sociedad Chilena de Obstetricia y Ginecologia",

number = "1",

}

Prevención de enfermedad hemolítica perinatal severa con inmunoglobulina intravenosa en paciente altamente sensibilizada. / Andueza, Catalina Villalobos; Balmaceda, Manuel José Monckeberg; González, Cristian Kottman et al.
In: Revista Chilena de Obstetricia y Ginecologia, Vol. 86, No. 1, 02.2021, p. 76-80.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Prevención de enfermedad hemolítica perinatal severa con inmunoglobulina intravenosa en paciente altamente sensibilizada

AU - Andueza, Catalina Villalobos

AU - Balmaceda, Manuel José Monckeberg

AU - González, Cristian Kottman

AU - Rocuant, Juan Carlos Arteaga

AU - Ebensperger, Enrique Oyarzún

PY - 2021/2

Y1 - 2021/2

N2 - Perinatal Hemolytic Disease is uncommon today due to its prevention. However, there are cases of highly sensitized mothers who wish to have a child, that forces this desired pregnancy to be controlled in a special way and be subjected to invasive procedures not exempt from fetal morbidity and mortality. Prenatal use of human inmunoglobulin in the mother may represent a therapeutic alternative. We present a case in which its use prevented the development of intrauterine disease and favored a good neonatal evolution despite the fact that the initial prognosis was very adverse.

AB - Perinatal Hemolytic Disease is uncommon today due to its prevention. However, there are cases of highly sensitized mothers who wish to have a child, that forces this desired pregnancy to be controlled in a special way and be subjected to invasive procedures not exempt from fetal morbidity and mortality. Prenatal use of human inmunoglobulin in the mother may represent a therapeutic alternative. We present a case in which its use prevented the development of intrauterine disease and favored a good neonatal evolution despite the fact that the initial prognosis was very adverse.

KW - Cordocentesis

KW - Immunoglobulin

KW - Intrauterine transfusion

KW - Perinatal hemolytic disease

KW - Rh(D) isoinmmunization

UR - https://www.scopus.com/pages/publications/85105532760

U2 - 10.4067/S0717-75262021000100076

DO - 10.4067/S0717-75262021000100076

M3 - Article

AN - SCOPUS:85105532760

SN - 0048-766X

VL - 86

SP - 76

EP - 80

JO - Revista Chilena de Obstetricia y Ginecologia

JF - Revista Chilena de Obstetricia y Ginecologia

IS - 1

ER -

Prevención de enfermedad hemolítica perinatal severa con inmunoglobulina intravenosa en paciente altamente sensibilizada

Abstract

Bibliographical note

UN SDGs

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