Prevalence of meningococcal carriage in children and adolescents aged 10-19 years in Chile in 2013

Janepsy Díaz, Marcela Cárcamo, Mabel Seoane, Paola Pidal, Gabriel Cavada, Rodrigo Puentes, Solana Terrazas, Pamela Araya, Ana B. Ibarz-Pavon, Macarena Manríquez, Juan C. Hormazábal, Salvador Ayala, María T. Valenzuela

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


In 2011, Chile experienced an increase in the number of cases of IMD caused by Neisseria meningitidis group W. This epidemiological scenario prompted authorities to implement prevention strategies. As part of these strategies, the Institute of Public Heath of Chile conducted a cross-sectional study to determine the prevalence of pharyngeal carriage of N. meningitidis in a representative sample of healthy children and adolescents aged 10-19 years.The identification of presumptive N. meningitidis strains was performed by testing carbohydrate utilization in the National Reference Laboratory at the ISP. Association of meningococcal carriage with risk factors was analyzed by calculating the Odds Ratio. Selected variables were included in a logistic model for risk analyses.The prevalence of carriage of N. meningitidis was 6.5% (CI: 5.7-7.3%). Older age (carriers: 14.2 ± 0.29 vs. non-carriers: 13.8 ± 0.08 years old; p = 0.009), cohabitation with children (carriers: 0.9 ± 0.13 vs. non-carriers: 0.7 ± 0.03; p = 0.028), number of smoking cohabitants (carriers: 0.55 ± 0.13 vs. non-carriers: 0.44 ± 0.03) and frequent attendance to crowded social venues (carriers: 49% vs. non-carriers: 37%; p = 0.008) were determined to favor carriage. Statistical modeling showed that meningococcal carriage was associated with older age (OR: 1.077, p-value: 0.002) and cohabitation with children (OR: 1.182, p-value: 0.02).
Original languageAmerican English
Pages (from-to)506-515
Number of pages10
JournalJournal of Infection and Public Health
Issue number4
StatePublished - 1 Jul 2016
Externally publishedYes


  • IMD
  • Meningococcal carriage
  • Multivariate logistic regression
  • Neisseria meningitidis
  • Prevalence
  • Risk factors

Fingerprint Dive into the research topics of 'Prevalence of meningococcal carriage in children and adolescents aged 10-19 years in Chile in 2013'. Together they form a unique fingerprint.

Cite this