PARTE I: NOCIONES BÁSICAS DE INMUNOLOGÍA SUSTAINED PERINATAL INFLAMMATORY SYNDROME OF THE EXTREME PRETERM INFANT. IMPORTANT FACTOR OF MORBIDITY AND MORTALITY IN THE EXTREMELY PRETERM INFANT. PART I: BASICS OF IMMUNOLOGY

Hernán Villalón*, Marie Chantal Caussade, María de los Ángeles Vial, Stefanie Pantoja, Natalia Vergara, Juan José Escobar

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

The inflammatory response associated with extreme preterm birth plays a relevant role in the prognosis of the newborn. The immaturity of the immune system fails to modulate the pro-inflammatory and anti-inflammatory mechanisms, triggering secondary damage with short, medium and long term sequelae. Objective: to review the immunological mechanisms involved in the sustained perinatal inflammatory syndrome, presenting possible prevention and treatment targets.

Translated title of the contributionSÍNDROME INFLAMATORIO PERINATAL PERSISTENTE. IMPORTANTE FACTOR DE MORBIMORTALIDAD EN EL PREMATURO EXTREMO
Original languageEnglish
Pages (from-to)664-671
Number of pages8
JournalRevista Medica Clinica Las Condes
Volume32
Issue number6
DOIs
StatePublished - 1 Nov 2021

Bibliographical note

Publisher Copyright:
© 2021

Keywords

  • Extreme Preterm
  • Immunological Basis
  • Inflammation
  • Sequels
  • Sustained Perinatal Inflammatory Syndrome

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