Outbreak due to Serratia marcescens associated with intrinsic contamination of aqueous chlorhexidine

Beatrice Hervé, May Chomali, Cecilia Gutiérrez, Mariana Luna, Jeannette Rivas, Rodrigo Blamey, Ricardo Espinoza, Giannina Izquierdo, Catalina Cabezas, Claudia Álvarez, Sebastián De La Fuente

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Serratia marcescens is a widely distributed gram-negative rod, often associated to nosocomial infections. Some outbreaks linked to contaminated antiseptic solutions have been reported. In this study we report a nosocomial outbreak of surgical site infection and catheter insertion site infection due to S. marcescens. 33 patients with positive cultures were studied after an index case was identified. Epidemiological, microbiological and molecular analysis demostrated an intrinsic contamination of alcohol free chlorhexidine solution as causal factor. Positive cultures were associated with 13 clinical infections, 9 colonized patients, 6 pseudobacteremia episodes and 5 patients without documented exposure. Hospital and national recall of contaminated chlorhexidine solution was performed after this study. Intrinsic contamination of antiseptic solutions is an infrequent cause of nosocomial infections with major epidemiological relevance.

Translated title of the contributionOutbreak due to Serratia marcescens associated with intrinsic contamination of aqueous chlorhexidine
Original languageSpanish
Pages (from-to)517-522
Number of pages6
JournalRevista Chilena de Infectologia
Volume32
Issue number5
DOIs
StatePublished - Oct 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2015, Sociedad Chilena de Infectologia. All rights reserved.

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