Abstract
Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.
Translated title of the contribution | Osteonecrosis of the jaws |
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Original language | Spanish |
Pages (from-to) | 983-991 |
Number of pages | 9 |
Journal | Revista Medica de Chile |
Volume | 148 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2020 |
Bibliographical note
Publisher Copyright:© 2020 Sociedad Medica de Santiago. All rights reserved.
Keywords
- Angiogenesis Inhibitors
- Bisphosphonate-Associated Osteonecrosis of the Jaw
- Bone Density Conservation Agents
- Diphosphonates
- Osteonecrosis