Osteonecrosis de los maxilares asociada a medicamentos: Revisión de la literatura y propuesta para la prevención y manejo

Translated title of the contribution: Osteonecrosis of the jaws

Camila Foncea, Kristine von Bischhoffshausen, Cristián Teuber, Hernán Ramírez, Ignacio Goñi, Cesar Sánchez, Ignacio N. Retamal, Alex Vargas*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.

Translated title of the contributionOsteonecrosis of the jaws
Original languageSpanish
Pages (from-to)983-991
Number of pages9
JournalRevista Medica de Chile
Volume148
Issue number7
DOIs
StatePublished - Jul 2020

Bibliographical note

Publisher Copyright:
© 2020 Sociedad Medica de Santiago. All rights reserved.

Keywords

  • Angiogenesis Inhibitors
  • Bisphosphonate-Associated Osteonecrosis of the Jaw
  • Bone Density Conservation Agents
  • Diphosphonates
  • Osteonecrosis

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