Neurogastroenterology and motility disorders in patients with cirrhosis

Francisco Idalsoaga; Gustavo Ayares; Hanna Blaney; Daniel Cabrera; Javier Chahuan; Hugo Monrroy; Ayah Matar; Houssam Halawi; Marco Arrese; Juan Pablo Arab; Luis Antonio Díaz

doi:10.1097/HC9.0000000000000622

Neurogastroenterology and motility disorders in patients with cirrhosis

Francisco Idalsoaga, Gustavo Ayares, Hanna Blaney, Daniel Cabrera, Javier Chahuan, Hugo Monrroy, Ayah Matar, Houssam Halawi, Marco Arrese, Juan Pablo Arab^*, Luis Antonio Díaz^*

^*Corresponding author for this work

Centro de Investigación e Innovación Biomédica

Research output: Contribution to journal › Review article › peer-review

Abstract

Neurogastroenterology and motility disorders are complex gastrointestinal conditions that are prevalent worldwide, particularly affecting women and younger individuals. These conditions significantly impact the quality of life of people suffering from them. There is increasing evidence linking these disorders to cirrhosis, with a higher prevalence compared to the general population. However, the link between neurogastroenterology and motility disorders and cirrhosis remains unclear due to undefined mechanisms. In addition, managing these conditions in cirrhosis is often limited by the adverse effects of drugs commonly used for these disorders, presenting a significant clinical challenge in the routine management of patients with cirrhosis. This review delves into this connection, exploring potential pathophysiological links and clinical interventions between neurogastroenterology disorders and cirrhosis.

Original language	English
Article number	10.1097/HC9.0000000000000622
Journal	Hepatology Communications
Volume	9
Issue number	1
DOIs	https://doi.org/10.1097/HC9.0000000000000622
State	Published - 7 Jan 2025

Bibliographical note

Publisher Copyright:
© 2025 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Association for the Study of Liver Diseases.

Keywords

cirrhosis
gut-brain axis
liver cirrhosis
liver diseases
neurogastroenterology

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title = "Neurogastroenterology and motility disorders in patients with cirrhosis",

abstract = "Neurogastroenterology and motility disorders are complex gastrointestinal conditions that are prevalent worldwide, particularly affecting women and younger individuals. These conditions significantly impact the quality of life of people suffering from them. There is increasing evidence linking these disorders to cirrhosis, with a higher prevalence compared to the general population. However, the link between neurogastroenterology and motility disorders and cirrhosis remains unclear due to undefined mechanisms. In addition, managing these conditions in cirrhosis is often limited by the adverse effects of drugs commonly used for these disorders, presenting a significant clinical challenge in the routine management of patients with cirrhosis. This review delves into this connection, exploring potential pathophysiological links and clinical interventions between neurogastroenterology disorders and cirrhosis.",

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AU - Idalsoaga, Francisco

AU - Ayares, Gustavo

AU - Blaney, Hanna

AU - Cabrera, Daniel

AU - Chahuan, Javier

AU - Monrroy, Hugo

AU - Matar, Ayah

AU - Halawi, Houssam

AU - Arrese, Marco

AU - Arab, Juan Pablo

AU - Díaz, Luis Antonio

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AB - Neurogastroenterology and motility disorders are complex gastrointestinal conditions that are prevalent worldwide, particularly affecting women and younger individuals. These conditions significantly impact the quality of life of people suffering from them. There is increasing evidence linking these disorders to cirrhosis, with a higher prevalence compared to the general population. However, the link between neurogastroenterology and motility disorders and cirrhosis remains unclear due to undefined mechanisms. In addition, managing these conditions in cirrhosis is often limited by the adverse effects of drugs commonly used for these disorders, presenting a significant clinical challenge in the routine management of patients with cirrhosis. This review delves into this connection, exploring potential pathophysiological links and clinical interventions between neurogastroenterology disorders and cirrhosis.

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Neurogastroenterology and motility disorders in patients with cirrhosis

Abstract

Bibliographical note

Keywords

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