TY - JOUR
T1 - Mental disorders & self-injurious thoughts and behaviors predict high risk of role impairment among university students - results from the world mental health international college student initiative
AU - Alonso, Jordi
AU - Petukhova, Maria V.
AU - Lee, Sue
AU - Sampson, Nancy A.
AU - Altwaijri, Yasmin A.
AU - AlHadi, Ahmad N.
AU - Al-Saud, Nouf K.
AU - Andersson, Claes
AU - Auerbach, Randy P.
AU - Ballester, Laura
AU - Bantjes, Jason
AU - Bendtsen, Marcus
AU - Benjet, Corina
AU - Berman, Anne H.
AU - Carrasco, Paula
AU - Chan, Silver C.N.
AU - Cohut, Irina
AU - Crockett, Marcelo A.
AU - Cuijpers, Pim
AU - David, Oana A.
AU - Dong, Dong
AU - Gaete, Jorge
AU - Felez-Nobrega, Mireia
AU - García Forero, Carlos
AU - Gili, Margalida
AU - Gutiérrez-García, Raúl A.
AU - Haro, Josep Maria
AU - Hunt, Xanthe
AU - Langer, Álvaro I.
AU - Léniz, Irene
AU - Liu, Yan
AU - Mac-Ginty, Scarlett
AU - Martínez, Vania
AU - Mason, Andre
AU - Miranda-Mendizabal, Andrea
AU - Núñez, Daniel
AU - Papasteri, Claudiu C.
AU - Piqueras, José A.
AU - Popescu, Codruta A.
AU - Rapsey, Charlene
AU - Rodriguez-Jimenez, Tiscar
AU - Saal, Wylene
AU - Siu, Oi ling
AU - Stein, Dan J.
AU - Struijs, Sascha Y.
AU - T.Tomoiaga, Cristina
AU - Wong, Samuel Y.S.
AU - Vilagut, Gemma
AU - Kessler, Ronald C.
N1 - Publisher Copyright:
Copyright © 2025. Published by Elsevier B.V.
PY - 2026/3/15
Y1 - 2026/3/15
N2 - Objective We examined psychopathological conditions accounting for the highest risk of role impairment among university students. Method Cross-sectional online survey of first-year students (60 universities, 10 countries) assessing role impairment due to emotional problems in previous 30 days with the 3-item emotional subscale of the VR-36. Cross-tabulations and Poisson regression examined associations between 12 psychopathological conditions (8 probable mental disorders and 4 SITB) and socio-demographics with “significant role impairment” (“most”/”all of the time” in 2+ VR-36 items). We used machine learning methods to predict probabilities (risk) of significant role impairment based on the 12 psychopathological conditions. Observed prevalence of significant role impairment was examined within and across the 20 population ventiles to assess risk concentration using sensitivity (SN) and positive predictive value (PPV). Results 43,990 students responded to the survey (median age = 19, IQR = 18–23). 27.1 % had significant role impairment due to emotional problems and 65.8 % had at least one psychopathological condition. Students with one or more of these conditions were more likely to have significant impairment than those without (RR = 3.9; 95 %CI: 3.6–4.2). In multivariable analyses, probable Depression and Bipolar disorders were the strongest correlates of significant impairment. Most (69.6 %) of the observed significant role impairment occurred among the roughly 35 % of respondents with highest predicted risk (PPV = 53.2 %). Conclusion Significant role impairment due to emotional problems is highly prevalent among university students. High risk of significant role impairment concentrates in one third of the students, those with several psychopathological conditions. Assessing these conditions should help identifying highest role impairment risk university students.
AB - Objective We examined psychopathological conditions accounting for the highest risk of role impairment among university students. Method Cross-sectional online survey of first-year students (60 universities, 10 countries) assessing role impairment due to emotional problems in previous 30 days with the 3-item emotional subscale of the VR-36. Cross-tabulations and Poisson regression examined associations between 12 psychopathological conditions (8 probable mental disorders and 4 SITB) and socio-demographics with “significant role impairment” (“most”/”all of the time” in 2+ VR-36 items). We used machine learning methods to predict probabilities (risk) of significant role impairment based on the 12 psychopathological conditions. Observed prevalence of significant role impairment was examined within and across the 20 population ventiles to assess risk concentration using sensitivity (SN) and positive predictive value (PPV). Results 43,990 students responded to the survey (median age = 19, IQR = 18–23). 27.1 % had significant role impairment due to emotional problems and 65.8 % had at least one psychopathological condition. Students with one or more of these conditions were more likely to have significant impairment than those without (RR = 3.9; 95 %CI: 3.6–4.2). In multivariable analyses, probable Depression and Bipolar disorders were the strongest correlates of significant impairment. Most (69.6 %) of the observed significant role impairment occurred among the roughly 35 % of respondents with highest predicted risk (PPV = 53.2 %). Conclusion Significant role impairment due to emotional problems is highly prevalent among university students. High risk of significant role impairment concentrates in one third of the students, those with several psychopathological conditions. Assessing these conditions should help identifying highest role impairment risk university students.
KW - mental disorders
KW - risk concentration
KW - risk prediction
KW - role impairment
KW - self-injurious thoughts and behaviors
KW - targeted interventions
KW - university students
UR - https://www.scopus.com/pages/publications/105024885795
U2 - 10.1016/j.jad.2025.120847
DO - 10.1016/j.jad.2025.120847
M3 - Article
C2 - 41371359
AN - SCOPUS:105024885795
SN - 0165-0327
VL - 397
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
M1 - 120847
ER -