Magnitude of social determinants in the risk of death from tuberculosis in Central-west Brazil

Translated title of the contribution: Magnitude of social determinants in the risk of death from tuberculosis in Central-west Brazil

Josilene Dália Alves*, Luiz Henrique Arroyo, Marcos Augusto Moraes Arcoverde, Denisse Cartagena-Ramos, Thais Zamboni Berra, Luana Seles Alves, Antônio Carlos Vieira Ramos, Miguel Fuentealba-Torres, Ivaneliza Simionato de Assis, Regina Célia Fiorati, Carla Nunes, Ricardo Alexandre Arcêncio

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Objective: To evaluate the magnitude of social determinants in areas of risk of mortality due to tuberculosis in a high incidence city. Method: Ecological study, which recruited the cases of tuberculosis deaths registered between 2006 and 2016 in the capital of Mato Grosso-Brazil. The social determinants were obtained from the Human Development Units. Sweep statistics were used to identify areas of risk of mortality due to tuberculosis. Principal component analysis was carried out to identify dimensions of social determinants. Multiple logistic regression was applied to verify associations between the dimensions of social determinants and the risk of mortality from tuberculosis. A 5% error was fixed. The standard error was established at 5% for all statistical tests. Results: A total of 225 deaths due to tuberculosis were registered in the period, distributed heterogeneously in the space. A cluster of risk for tuberculosis mortality was identified, with RR = 2.09 (95%CI: 1.48-2.94; p = 0.04). Social determinants, low educational level and poverty were associated with the risk of mortality due to tuberculosis (OR: 2.92; 95%CI: 1.17-7.28). Income had a negative association with the risk of mortality due to tuberculosis (OR: 0.05; 95%CI: 0.00-0.70). The value of the ROC curve of the model was 92.1%. Conclusions: The results confirmed that the risk of mortality due to tuberculosis is a problem associated with social determinants. Health policies and social protection programmes can collaborate to address this problem.

Translated title of the contributionMagnitude of social determinants in the risk of death from tuberculosis in Central-west Brazil
Original languageEnglish
Pages (from-to)171-178
Number of pages8
JournalGaceta Sanitaria
Volume34
Issue number2
DOIs
StatePublished - 1 Mar 2020
Externally publishedYes

Bibliographical note

Funding Information:
El estudio fue financiado por la Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) mediante el proceso 2015/17586-3, y por el Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) mediante los procesos 305236/2015-6 y 141716/2017-7.

Publisher Copyright:
© 2019 SESPAS

Keywords

  • Brazil
  • Mortality
  • Mycobacterium tuberculosis
  • Social determinants of health
  • Tuberculosis

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