Lipid profile in healthy pregnant women from three regions in Chile

Pablo C. Olmos, Manuel O. Escalona, Sebastián Illanes, Javier B. Caradeux, Gabriel Mardones, Daniela U. Olivari, Leoncio V. Fuentes, Ana B. Acosta, Attilio R. Rigotti, Dolores Busso, José M. Santos, José L. Poblete, Claudio P.G. Vera, Cristián J. Belmar, Denisse A. Goldenberg, Bárbara C. Samith, Ian L. Niklitschek, Nicolás F. Mertens

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background: In normal human pregnancy, maternal lipids can modify the rate of fetal growth, particularly in pregnancies with Gestational Diabetes Mellitus (GDM). These lipids change continuously their serum concentration in the mother along the pregnancy. Aim: To calculate tables and curves of normal serum lipids, according to gestational age, in healthy Chilean pregnant women. Methods: We measured total cholesterol (CT), LDL-cholesterol (LDL-C), triglycerides (TG), HDL-Cholesterol (HDL-C), and Non-Esterified Fatty Acids (NEFA) in 94 young and healthy pregnant women (< 33 years, mean age 27.6 ± 6.2 years), with normal pregestational Body Mass Index (BMI, 20.0-24.9 Kg/m2 , mean value= 23.3 ± 2.0 Kg/m2). The women of the study were patients of 5 hospitals: Hospital Parroquial de San Bernardo, Santiago (n=55), Hospital de Talca (n=2); Hospital del Profesor, Santiago (n=18); Hospital Regional de Concepción (n=9) and Hospital Clínico de la Pontificia Universidad Católica de Chile (n=10). Results: For each one of the lipids, we calculated curves of 50th, 90th and 10th percentiles, both in mg/dL and mmol/L (the NEFA were expressed only in mmol/L). The mathematical functions of the curves of polynomial regression of all lipids were included in the manuscript, in order to facilitate their reproduction. Conclusions: We calculated tables and curves of normal maternal serum lipids in relation to gestational, in order to make these available for use in the care of Chilean pregnant women.

Translated title of the contributionLipid profile in healthy pregnant women from three regions in Chile
Original languageSpanish
Pages (from-to)416-420
Number of pages5
JournalRevista Chilena de Obstetricia y Ginecologia
Volume79
Issue number5
StatePublished - 1 Sep 2014

Fingerprint Dive into the research topics of 'Lipid profile in healthy pregnant women from three regions in Chile'. Together they form a unique fingerprint.

Cite this