Intraoral sclerosing perineurioma: a case report and review of the literature

Wilfredo Alejandro González-Arriagada, Jorge Esquiche Leon, Pablo Agustin Vargas, Oslei Paes de Almeida, Marcio Ajudarte Lopes*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Sclerosing perineurioma is an extraneural soft tissue lesion that has been reported in the extremities of young adults. It is composed of oval epithelioid or plump spindled cells scattered to form ill-defined fascicles in a storiform, whorled, or trabecular pattern and dermal sclerosis represented by thickened collagen bundles in a lamellar array that express epithelial membrane antigen and are negative for S-100 protein. The treatment is surgical excision, and no recurrence or metastases are expected. Herein is presented the first case of intraoral sclerosing perineurioma of the lower lip, emphasizing its histopathologic and immunohistochemical features.

Original languageEnglish
Pages (from-to)e46-e52
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
Issue number5
StatePublished - May 2010
Externally publishedYes


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