Keyphrases
Transcriptional Regulator
100%
Osteoblast
100%
Enhancer of Zeste Homolog 2 (EZH2)
100%
Hedgehog Signaling Pathway
100%
Bivalent Domains
100%
Integrated Pathways
100%
Tazemetostat
80%
H3K27me3
60%
Lysine
60%
Bone Formation
40%
Osteogenesis
40%
Regulatory Genes
40%
Osteogenic Differentiation
40%
Histone H3
40%
Epigenomics
40%
MC3T3
20%
RNA Sequencing (RNA-seq)
20%
Synergize
20%
Epigenetics
20%
Chromatin Immunoprecipitation (ChIP)
20%
Bone Loss
20%
Regulatory Domain
20%
Preosteoblast
20%
Functional Analysis
20%
Transcriptomics
20%
Osteoblast Differentiation
20%
H3K4me3
20%
Trimethylation
20%
Methyltransferase
20%
Gli2
20%
Hedgehog
20%
Clinical Indications
20%
Developmental Genes
20%
Cooperativity
20%
Bone Mass Accrual
20%
Repurposing
20%
Pathway-based Approach
20%
Mechanistic Effect
20%
Osteoblast Precursors
20%
EPZ6438
20%
Enhancer of Zeste Homolog 2 Inhibitors
20%
Silencing RNA
20%
Bivalent Genes
20%
Epithelioid Sarcoma
20%
Adenylyl Cyclase
20%
Sarcoma Treatment
20%
CAMP Signaling
20%
Gli1
20%
Hedgehog-Gli
20%
Pathway Inhibitors
20%
Medicine and Dentistry
Osteoblast
100%
Hedgehog Signaling
100%
Transcription Factor EZH2
100%
Tazemetostat
83%
Lysine
50%
Ossification
33%
Bone Development
33%
Regulator Gene
33%
Histone H3
33%
Signal Transduction
16%
In Vitro
16%
Maturation
16%
Cooperation
16%
Osteolysis
16%
RNA Sequencing
16%
Bone Mass
16%
Methyltransferase
16%
Developmental Gene
16%
Enhancer Region
16%
cAMP Signaling
16%
Chromatin Immunoprecipitation
16%
MC3T3
16%
Adenylate Cyclase
16%
Epithelioid Sarcoma
16%
Biochemistry, Genetics and Molecular Biology
Osteoblast
100%
Transcription Factor EZH2
100%
Hedgehog Signaling Pathway
100%
Lysine
50%
Bone Development
33%
Histone H3
33%
Hedgehog
33%
Ossification
33%
Regulatory Gene
33%
Enhancer Region
16%
Maturation
16%
Cooperation
16%
RNA Sequencing
16%
Epigenetics
16%
Chromatin Immunoprecipitation
16%
Small Interfering RNA
16%
Transcription
16%
Methyltransferase
16%
Osteolysis
16%
Bone Mass
16%
cAMP Signaling
16%
Developmental Gene
16%
Adenylate Cyclase
16%
Pharmacology, Toxicology and Pharmaceutical Science
Transcription Factor EZH2
100%
Hedgehog
100%
Tazemetostat
83%
Lysine
50%
Histone H3
33%
Methyltransferase
16%
Adenylate Cyclase
16%
Chromatin Immunoprecipitation
16%
Epithelioid Sarcoma
16%