TY - JOUR
T1 - Incidence of type 1 diabetes in Chilean children between 2006 and 2021
T2 - significant increase during the COVID-19 pandemic
AU - Tampe, Ingeborg
AU - Garfias, Carolina
AU - Borzutzky, Arturo
AU - Slaibe, Lissette
AU - García, Hernán
N1 - © 2023, Springer-Verlag Italia S.r.l., part of Springer Nature.
PY - 2023/8/14
Y1 - 2023/8/14
N2 - Aims: An increase in type 1 diabetes (T1D) incidence has been observed in several countries during the COVID-19 pandemic. The objective of this study is to determine T1D incidence trends in Chilean children between 2006 and 2021, and specifically evaluate the effect of the COVID-19 pandemic in this population. Methods: We reviewed mandatory notifications of T1D in Chile's public and private health system in youth < 20 years between 2006 and 2021, and compared COVID-19 pre-pandemic and pandemic incidence. Results: In Chile, 9472 new T1D cases in children were confirmed between 2006 and 2021. The mean annual T1D incidence in the entire period was 12.7/100,000 inhabitants, with an incidence of 11.7/100,000 between 2006 and 2019 vs. 20.2/100,000 during 2020–2021 (β = 0.691, [95%CI 0.479–0903], p < 0.001.) The highest incidence was observed in the 10–14 years age group, but a significant increasing incidence was observed in all age groups. The second year of the COVID-19 pandemic, 2021, had the highest incidence rate of the study period. While a 5% mean annual increase was observed between 2006 and 2019, in 2021 the T1D incidence jumped 28.5% compared with the two previous years. We found a higher T1D incidence in population with private insurance than public insurance (14.8 vs. 11.7/100.000, respectively, RR = 1.26 [95%CI 1.03–1.53], p < 0.027). Conclusions: T1D incidence rates in Chilean youth doubled between 2006 and 2018, subsequently presenting a striking increase during the COVID-19 pandemic.
AB - Aims: An increase in type 1 diabetes (T1D) incidence has been observed in several countries during the COVID-19 pandemic. The objective of this study is to determine T1D incidence trends in Chilean children between 2006 and 2021, and specifically evaluate the effect of the COVID-19 pandemic in this population. Methods: We reviewed mandatory notifications of T1D in Chile's public and private health system in youth < 20 years between 2006 and 2021, and compared COVID-19 pre-pandemic and pandemic incidence. Results: In Chile, 9472 new T1D cases in children were confirmed between 2006 and 2021. The mean annual T1D incidence in the entire period was 12.7/100,000 inhabitants, with an incidence of 11.7/100,000 between 2006 and 2019 vs. 20.2/100,000 during 2020–2021 (β = 0.691, [95%CI 0.479–0903], p < 0.001.) The highest incidence was observed in the 10–14 years age group, but a significant increasing incidence was observed in all age groups. The second year of the COVID-19 pandemic, 2021, had the highest incidence rate of the study period. While a 5% mean annual increase was observed between 2006 and 2019, in 2021 the T1D incidence jumped 28.5% compared with the two previous years. We found a higher T1D incidence in population with private insurance than public insurance (14.8 vs. 11.7/100.000, respectively, RR = 1.26 [95%CI 1.03–1.53], p < 0.027). Conclusions: T1D incidence rates in Chilean youth doubled between 2006 and 2018, subsequently presenting a striking increase during the COVID-19 pandemic.
KW - COVID-19
KW - Epidemiology
KW - Incidence
KW - Type 1 diabetes
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85167891622&origin=resultslist&sort=plf-f&src=s&sid=357ead5eab99ec9c754cb52d872ec6a5&sot=b&sdt=b&s=TITLE-ABS-KEY%28Incidence+of+type+1+diabetes+in+Chilean+children+between+2006+and+2021%29&sl=85&sessionSearchId=357ead5eab99ec9c754cb52d872ec6a5&relpos=0
U2 - 10.1007/s00592-023-02163-3
DO - 10.1007/s00592-023-02163-3
M3 - Article
SN - 0940-5429
VL - 29
SP - 29
EP - 34
JO - Acta Diabetologica
JF - Acta Diabetologica
IS - 34
ER -
