Hepatobiliary manifestations in inflammatory bowel disease: A practical approach

Paulina Núñez F*, Fabiola Castro, Gabriel Mezzano, Rodrigo Quera, Diego Diaz, Lorena Castro

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Inflammatory bowel diseases (IBD) are associated with various hepatobiliary disorders. They can occur at any moment in the course of the disease or associated with the treatment. The prevalence of liver dysfunction can reach up to 50% in different studies. Nonalcoholic fatty liver disease is considered the most common hepatobiliary complication in IBD, while primary sclerosing cholangitis is the most specific. Management of hepatic manifestations in IBD involves a multidisciplinary approach that includes a high index of suspicion and joint management with hepatologists. The medical confrontation with abnormal liver tests must include an exhaustive study to determine if these patterns can be related to IBD, associated diseases or to the therapies used.

Original languageEnglish
Pages (from-to)319-337
Number of pages19
JournalWorld Journal of Hepatology
Issue number2
StatePublished - 27 Feb 2022

Bibliographical note

Publisher Copyright:
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.


  • Extraintestinal manifestations
  • Hepatic steatosis
  • Inflammatory bowel disease
  • Liver toxicity
  • Sclerosing primary cholangitis


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