Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results

C. von Muhlenbrock; P. Núñez; K. Herrera; N. Pacheco; R. Quera

doi:10.1016/j.rgmx.2025.03.001

Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results

C. von Muhlenbrock^*, P. Núñez, K. Herrera, N. Pacheco, R. Quera

^*Corresponding author for this work

Clínica Universidad de los Andes

Research output: Contribution to journal › Article › peer-review

Abstract

Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.

Translated title of the contribution	Trasplante de microbiota fecal mediante colonoscopia para el manejo del síndrome de intestino irritable refractario: resultados preliminares
Original language	English
Journal	Revista de Gastroenterologia de Mexico
DOIs	https://doi.org/10.1016/j.rgmx.2025.03.001
State	Accepted/In press - 2025

Bibliographical note

Publisher Copyright:
© 2025 Asociación Mexicana de Gastroenterología

Keywords

Colonoscopy
Fecal microbiota transplantation
Irritable bowel syndrome
Microbiota
Treatment

Access to Document

10.1016/j.rgmx.2025.03.001

Cite this

@article{473a827d0caa4342ae08fabe2d842354,

title = "Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results",

abstract = "Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.",

keywords = "Colonoscopy, Fecal microbiota transplantation, Irritable bowel syndrome, Microbiota, Treatment",

author = "{von Muhlenbrock}, C. and P. N{\'u}{\~n}ez and K. Herrera and N. Pacheco and R. Quera",

note = "Publisher Copyright: {\textcopyright} 2025 Asociaci{\'o}n Mexicana de Gastroenterolog{\'i}a",

year = "2025",

doi = "10.1016/j.rgmx.2025.03.001",

language = "English",

journal = "Revista de Gastroenterologia de Mexico",

issn = "0375-0906",

publisher = "Asociacion Mexicana de Gastroenterologia",

}

TY - JOUR

T1 - Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome

T2 - Preliminary results

AU - von Muhlenbrock, C.

AU - Núñez, P.

AU - Herrera, K.

AU - Pacheco, N.

AU - Quera, R.

PY - 2025

Y1 - 2025

N2 - Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.

AB - Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.

KW - Colonoscopy

KW - Fecal microbiota transplantation

KW - Irritable bowel syndrome

KW - Microbiota

KW - Treatment

UR - http://www.scopus.com/inward/record.url?scp=105002909647&partnerID=8YFLogxK

U2 - 10.1016/j.rgmx.2025.03.001

DO - 10.1016/j.rgmx.2025.03.001

M3 - Article

AN - SCOPUS:105002909647

SN - 0375-0906

JO - Revista de Gastroenterologia de Mexico

JF - Revista de Gastroenterologia de Mexico

ER -

Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this