Fecal microbiota transplantation: First case report in Chile and review

Ricardo Espinoza, Rodrigo Quera, Lital Meyer, Daniela Rivera

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Clostridium diffcile (CD) infection is increasing in frequency and severity in in-hospital and outpatient clinical settings, with a recurrence that can reach 30% after frst episode. The recurrences are usually treated with longer courses of metronidazole or vancomycin. Other treatments have been used, such as probiotics, fdaxomicin, rifaxi-min, immunoglobulins and monoclonal antibodies against toxins A and B. Fecal microbiota transplantation (FMT) has emerged as a promising strategy in this group of patients, with effectiveness greater than 90%. We present the frst case reported in Chile of this therapeutic strategy in a patient with Crohn´s disease and recurrent CD infection who presented after the fecal transplantation an Escherichia coli bacteremia, suggesting the need for caution in the use of this strategy. 10 months after the FMT the patient presented a new episode of E. coli bacteremia and two episodes of diarrhea due to CD infection, treated both of them with vancomycin with good clinical response.

Translated title of the contributionFecal microbiota transplantation: First case report in Chile and review
Original languageSpanish
Pages (from-to)477-482
Number of pages6
JournalRevista Chilena de Infectologia
Volume31
Issue number4
DOIs
StatePublished - 1 Aug 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2014, Sociedad Chilena de Infectologia. All rights reserved.

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