Expression and Distribution of Kallikrein-related Peptidases 5, 7, 8 and 10 in Normal Apocrine Gland of Canine Skin

Pamela Ehrenfeld; Carlos D. Figueroa; Luis Molina; Tania Koning; Myriam Velasco; Felipe A. Bustamante-Barrientos; Alexander Ortloff

doi:10.4067/S0717-95022023000100210

Expression and Distribution of Kallikrein-related Peptidases 5, 7, 8 and 10 in Normal Apocrine Gland of Canine Skin

Pamela Ehrenfeld, Carlos D. Figueroa, Luis Molina, Tania Koning, Myriam Velasco, Felipe A. Bustamante-Barrientos, Alexander Ortloff^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Apocrine glands are sweat glands that are located in the skin of the dog. Anal sac apocrine, circunanal apocrine, and mammary glands are considered modified apocrine structures, and there are about nine possible types of neoplasms and other tumors in the apocrine glands of the dog and cat, including cysts, adenoma, carcinoma, and adenocarcinoma. Thus, it is important to provide new markers to characterize these glands to improve the histopathological diagnosis. In this article, we describe the distribution of kallikrein-related peptidases 5, 7, 8, and 10 in the normal apocrine glands of the dog’s skin. These proteases have been shown to play a fundamental role in the homeostasis of the human skin barrier but have been scarcely studied in canine skin.

Translated title of the contribution	Expresión y Distribución de Péptidos Relacionados con la Calicreína 5, 7, 8 y 10 en Glándula Apocrina Normal de Piel Canina
Original language	English
Pages (from-to)	210-215
Number of pages	6
Journal	International Journal of Morphology
Volume	41
Issue number	1
DOIs	https://doi.org/10.4067/S0717-95022023000100210
State	Published - 1 Feb 2023

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Publisher Copyright:
© 2023, Universidad de la Frontera. All rights reserved.

Keywords

Apocrine gland
Dog
Kallikrein-related peptidases
KLKs

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10.4067/S0717-95022023000100210

Cite this

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title = "Expression and Distribution of Kallikrein-related Peptidases 5, 7, 8 and 10 in Normal Apocrine Gland of Canine Skin",

abstract = "Apocrine glands are sweat glands that are located in the skin of the dog. Anal sac apocrine, circunanal apocrine, and mammary glands are considered modified apocrine structures, and there are about nine possible types of neoplasms and other tumors in the apocrine glands of the dog and cat, including cysts, adenoma, carcinoma, and adenocarcinoma. Thus, it is important to provide new markers to characterize these glands to improve the histopathological diagnosis. In this article, we describe the distribution of kallikrein-related peptidases 5, 7, 8, and 10 in the normal apocrine glands of the dog{\textquoteright}s skin. These proteases have been shown to play a fundamental role in the homeostasis of the human skin barrier but have been scarcely studied in canine skin.",

keywords = "Apocrine gland, Dog, Kallikrein-related peptidases, KLKs",

author = "Pamela Ehrenfeld and Figueroa, \{Carlos D.\} and Luis Molina and Tania Koning and Myriam Velasco and Bustamante-Barrientos, \{Felipe A.\} and Alexander Ortloff",

year = "2023",

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doi = "10.4067/S0717-95022023000100210",

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T1 - Expression and Distribution of Kallikrein-related Peptidases 5, 7, 8 and 10 in Normal Apocrine Gland of Canine Skin

AU - Ehrenfeld, Pamela

AU - Figueroa, Carlos D.

AU - Molina, Luis

AU - Koning, Tania

AU - Velasco, Myriam

AU - Bustamante-Barrientos, Felipe A.

AU - Ortloff, Alexander

PY - 2023/2/1

Y1 - 2023/2/1

N2 - Apocrine glands are sweat glands that are located in the skin of the dog. Anal sac apocrine, circunanal apocrine, and mammary glands are considered modified apocrine structures, and there are about nine possible types of neoplasms and other tumors in the apocrine glands of the dog and cat, including cysts, adenoma, carcinoma, and adenocarcinoma. Thus, it is important to provide new markers to characterize these glands to improve the histopathological diagnosis. In this article, we describe the distribution of kallikrein-related peptidases 5, 7, 8, and 10 in the normal apocrine glands of the dog’s skin. These proteases have been shown to play a fundamental role in the homeostasis of the human skin barrier but have been scarcely studied in canine skin.

AB - Apocrine glands are sweat glands that are located in the skin of the dog. Anal sac apocrine, circunanal apocrine, and mammary glands are considered modified apocrine structures, and there are about nine possible types of neoplasms and other tumors in the apocrine glands of the dog and cat, including cysts, adenoma, carcinoma, and adenocarcinoma. Thus, it is important to provide new markers to characterize these glands to improve the histopathological diagnosis. In this article, we describe the distribution of kallikrein-related peptidases 5, 7, 8, and 10 in the normal apocrine glands of the dog’s skin. These proteases have been shown to play a fundamental role in the homeostasis of the human skin barrier but have been scarcely studied in canine skin.

KW - Apocrine gland

KW - Dog

KW - Kallikrein-related peptidases

KW - KLKs

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Expression and Distribution of Kallikrein-related Peptidases 5, 7, 8 and 10 in Normal Apocrine Gland of Canine Skin

Abstract

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Keywords

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