Detection of CD63+ micro-vesicles, placental alkaline phosphatase and angiogenic markers in gingival crevicular fluid in preeclamptic patients

Alejandra Chaparro; Edgardo Zúñiga; Dominique Gaedechens; Valeria Ramírez; c silva; P. Juan Kusanovic; Karla Silva; Gregory E. Rice; Sebastián Illanes

doi:10.1016/j.placenta.2015.07.347

Detection of CD63+ micro-vesicles, placental alkaline phosphatase and angiogenic markers in gingival crevicular fluid in preeclamptic patients

Alejandra Chaparro, Edgardo Zúñiga, Dominique Gaedechens, Valeria Ramírez, c silva, P. Juan Kusanovic, Karla Silva, Gregory E. Rice, Sebastián Illanes

Research output: Contribution to journal › Article › peer-review

Abstract

Preeclampsia (PE) is a maternal disease that clinically manifests in the second half of pregnancy, characterized by hypertension accompanied by proteinuria and generalized edema. Its complications have become one of the main causes of maternal and fetal morbidity and mortality in the world, causing nearly 40% of premature births delivered before 35 weeks of gestation PE is present in around 5–10% of all pregnant women worldwide and despite the amount of resources invested in the research and treatment of this pathology, it’s still barely predictable and thus difficult to manage clinically. The aim of this study was to determine utility of Cd63+ micro-vesicles, placental alkaline phosphatase and angiogenic biomarkers concentrations in gingival crevicular fluid (GCF) as biomarkers of preeclampsia.

Original language	English
Pages (from-to)	A53
Number of pages	1
Journal	Placenta
Volume	9
Issue number	36
DOIs	https://doi.org/10.1016/j.placenta.2015.07.347
State	Published - Sep 2015

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title = "Detection of CD63+ micro-vesicles, placental alkaline phosphatase and angiogenic markers in gingival crevicular fluid in preeclamptic patients",

abstract = "Preeclampsia (PE) is a maternal disease that clinically manifests in the second half of pregnancy, characterized by hypertension accompanied by proteinuria and generalized edema. Its complications have become one of the main causes of maternal and fetal morbidity and mortality in the world, causing nearly 40% of premature births delivered before 35 weeks of gestation PE is present in around 5–10% of all pregnant women worldwide and despite the amount of resources invested in the research and treatment of this pathology, it{\textquoteright}s still barely predictable and thus difficult to manage clinically. The aim of this study was to determine utility of Cd63+ micro-vesicles, placental alkaline phosphatase and angiogenic biomarkers concentrations in gingival crevicular fluid (GCF) as biomarkers of preeclampsia.",

author = "Alejandra Chaparro and Edgardo Z{\'u}{\~n}iga and Dominique Gaedechens and Valeria Ram{\'i}rez and c silva and {Juan Kusanovic}, P. and Karla Silva and Rice, {Gregory E.} and Sebasti{\'a}n Illanes",

year = "2015",

month = sep,

doi = "10.1016/j.placenta.2015.07.347",

language = "English",

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publisher = "W.B. Saunders Ltd",

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TY - JOUR

T1 - Detection of CD63+ micro-vesicles, placental alkaline phosphatase and angiogenic markers in gingival crevicular fluid in preeclamptic patients

AU - Chaparro, Alejandra

AU - Zúñiga, Edgardo

AU - Gaedechens, Dominique

AU - Ramírez, Valeria

AU - silva, c

AU - Juan Kusanovic, P.

AU - Silva, Karla

AU - Rice, Gregory E.

AU - Illanes, Sebastián

PY - 2015/9

Y1 - 2015/9

N2 - Preeclampsia (PE) is a maternal disease that clinically manifests in the second half of pregnancy, characterized by hypertension accompanied by proteinuria and generalized edema. Its complications have become one of the main causes of maternal and fetal morbidity and mortality in the world, causing nearly 40% of premature births delivered before 35 weeks of gestation PE is present in around 5–10% of all pregnant women worldwide and despite the amount of resources invested in the research and treatment of this pathology, it’s still barely predictable and thus difficult to manage clinically. The aim of this study was to determine utility of Cd63+ micro-vesicles, placental alkaline phosphatase and angiogenic biomarkers concentrations in gingival crevicular fluid (GCF) as biomarkers of preeclampsia.

AB - Preeclampsia (PE) is a maternal disease that clinically manifests in the second half of pregnancy, characterized by hypertension accompanied by proteinuria and generalized edema. Its complications have become one of the main causes of maternal and fetal morbidity and mortality in the world, causing nearly 40% of premature births delivered before 35 weeks of gestation PE is present in around 5–10% of all pregnant women worldwide and despite the amount of resources invested in the research and treatment of this pathology, it’s still barely predictable and thus difficult to manage clinically. The aim of this study was to determine utility of Cd63+ micro-vesicles, placental alkaline phosphatase and angiogenic biomarkers concentrations in gingival crevicular fluid (GCF) as biomarkers of preeclampsia.

U2 - 10.1016/j.placenta.2015.07.347

DO - 10.1016/j.placenta.2015.07.347

M3 - Article

SN - 0143-4004

VL - 9

SP - A53

JO - Placenta

JF - Placenta

IS - 36

ER -

Detection of CD63+ micro-vesicles, placental alkaline phosphatase and angiogenic markers in gingival crevicular fluid in preeclamptic patients

Abstract

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