Dentin moisture does not influence postoperative sensitivity in posterior restorations: a double-blind randomized clinical trial

Andrea S Castro, Bianca M Maran, Mario F Gutiérrez, Eveline C Martini, Fabiana Ds Dreweck, Luján Mendez-Bauer, Alessandra Reis, Alessandro D Loguercio

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


PURPOSE: This double-blind, randomized clinical trial evaluated the influence of dentin moisture on postoperative sensitivity (POS) in posterior restorations using a simplified etch-and-rinse adhesive, until 12 months of clinical service.

METHODS: 90 restorations were inserted in 45 patients to treat carious lesions or to replace existing posterior restorations with a depth ≥ 3 mm. After cavity preparation, the simplified etch-and-rinse adhesive (Adper Single Bond 2) was applied on dry or wet dentin followed by a bulk-fill resin composite (Filtek Bulk Fill) under rubber dam isolation. The patient's spontaneous and stimulated POS was evaluated at baseline and after 7 days, 6 months, and 12 months of clinical evaluation. The secondary parameters (marginal discoloration, marginal adaptation, fracture and recurrence of caries) were evaluated by World Dental Federation (FDI) criteria after 7 days, 6 and 12 months of clinical evaluation.

RESULTS: No significant spontaneous and stimulated POS was observed when dry and wet dentin were compared (P> 0.05). A significant and higher risk of spontaneous POS (18.6%; 95% CI 9.7 to 32.6) occurred up to 48 hours after restoration placement for both groups when compared to all evaluation times (P< 0.03). However, the intensity of POS was mild at up to 48 hours with a difference between the dry and wet dentin groups (P> 0.79). When secondary parameters were evaluated, no significant difference between the groups were observed (P> 0.05).

CLINICAL SIGNIFICANCE: The moisture level of the dentin substrate in posterior restorations does not influence POS in bulk-fill resin composite posterior restorations when associated with an etch-and-rinse ethanol-based adhesive system.

Original languageEnglish
Pages (from-to)206-212
Number of pages7
JournalAmerican Journal of Dentistry
Issue number4
StatePublished - Aug 2020

Bibliographical note

Copyright©American Journal of Dentistry.


  • Composite Resins
  • Dental Caries
  • Dental Marginal Adaptation
  • Dental Restoration, Permanent
  • Dentin
  • Dentin Sensitivity
  • Dentin-Bonding Agents
  • Double-Blind Method
  • Humans
  • Resin Cements


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