Defectos congénitos de antitrombina III y proteínas S y C durante el embarazo

Rodrigo Enríquez R.; Carlos Rondini F.; Alvaro Sánchez M.; Carmen Montes I.; José Andrés Poblete L.; Jorge Neira M.; Enrique Oyarzún E.; Alfredo Germain A.

Defectos congénitos de antitrombina III y proteínas S y C durante el embarazo

Translated title of the contribution: Congenital defects of antithrombin III and proteins C and S during pregnancy. Report of ten cases

Rodrigo Enríquez R.^*, Carlos Rondini F., Alvaro Sánchez M., Carmen Montes I., José Andrés Poblete L., Jorge Neira M., Enrique Oyarzún E., Alfredo Germain A.

^*Corresponding author for this work

Clínica Universidad de los Andes

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We report 10 patients with congenital deficiencies of the natural anticoagulant proteins S, C and antithrombin III. Thirteen of a total of 30 pregnancies were managed at the perinatal branch of our department. We discuss the mechanism of action of these proteins and their role in thrombotic events. We analyze the most frequent thrombotic complications and we discuss the general guidelines for the investigation of a patient with a suspected congenital thrombophilia with special regard to its management during pregnancy, delivery and perinatal outcome.

Translated title of the contribution	Congenital defects of antithrombin III and proteins C and S during pregnancy. Report of ten cases
Original language	Spanish
Pages (from-to)	171-180
Number of pages	10
Journal	Revista Medica de Chile
Volume	127
Issue number	2
State	Published - Feb 1999

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@article{9b2e25ec97064bdf8277fe2d900fb95e,

title = "Defectos cong{\'e}nitos de antitrombina III y prote{\'i}nas S y C durante el embarazo",

abstract = "We report 10 patients with congenital deficiencies of the natural anticoagulant proteins S, C and antithrombin III. Thirteen of a total of 30 pregnancies were managed at the perinatal branch of our department. We discuss the mechanism of action of these proteins and their role in thrombotic events. We analyze the most frequent thrombotic complications and we discuss the general guidelines for the investigation of a patient with a suspected congenital thrombophilia with special regard to its management during pregnancy, delivery and perinatal outcome.",

keywords = "Anticoagulants, antithrombin III, Pregnancy complications, Protein C, Protein S",

author = "{Enr{\'i}quez R.}, Rodrigo and {Rondini F.}, Carlos and {S{\'a}nchez M.}, Alvaro and {Montes I.}, Carmen and {Poblete L.}, {Jos{\'e} Andr{\'e}s} and {Neira M.}, Jorge and {Oyarz{\'u}n E.}, Enrique and {Germain A.}, Alfredo",

year = "1999",

month = feb,

language = "Spanish",

volume = "127",

pages = "171--180",

journal = "Revista Medica de Chile",

issn = "0034-9887",

publisher = "Sociedad Medica de Santiago",

number = "2",

}

TY - JOUR

T1 - Defectos congénitos de antitrombina III y proteínas S y C durante el embarazo

AU - Enríquez R., Rodrigo

AU - Rondini F., Carlos

AU - Sánchez M., Alvaro

AU - Montes I., Carmen

AU - Poblete L., José Andrés

AU - Neira M., Jorge

AU - Oyarzún E., Enrique

AU - Germain A., Alfredo

PY - 1999/2

Y1 - 1999/2

N2 - We report 10 patients with congenital deficiencies of the natural anticoagulant proteins S, C and antithrombin III. Thirteen of a total of 30 pregnancies were managed at the perinatal branch of our department. We discuss the mechanism of action of these proteins and their role in thrombotic events. We analyze the most frequent thrombotic complications and we discuss the general guidelines for the investigation of a patient with a suspected congenital thrombophilia with special regard to its management during pregnancy, delivery and perinatal outcome.

AB - We report 10 patients with congenital deficiencies of the natural anticoagulant proteins S, C and antithrombin III. Thirteen of a total of 30 pregnancies were managed at the perinatal branch of our department. We discuss the mechanism of action of these proteins and their role in thrombotic events. We analyze the most frequent thrombotic complications and we discuss the general guidelines for the investigation of a patient with a suspected congenital thrombophilia with special regard to its management during pregnancy, delivery and perinatal outcome.

KW - Anticoagulants, antithrombin III

KW - Pregnancy complications

KW - Protein C

KW - Protein S

UR - http://www.scopus.com/inward/record.url?scp=0033072083&partnerID=8YFLogxK

M3 - Article

C2 - 10436697

AN - SCOPUS:0033072083

SN - 0034-9887

VL - 127

SP - 171

EP - 180

JO - Revista Medica de Chile

JF - Revista Medica de Chile

IS - 2

ER -

Defectos congénitos de antitrombina III y proteínas S y C durante el embarazo

Abstract

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