Abstract
Hepatitis A is an important public health problem in Chile. Childhood vaccination has reduced hepatitis A rates in several countries, prompting this evaluation of its cost-effectiveness in Chile. Using a Markov model, we project mass vaccination would reduce hepatitis A cases among birth cohort members and their personal contacts >80%. Vaccination costs of US$ 5.3-6.4 million would be offset by US$ 9.2-9.4 million reductions in disease costs. Further, approximately 70 fatal infections would be averted and >4600 quality-adjusted life years would be saved. This analysis supports the cost-effectiveness of universal childhood hepatitis A vaccination in Chile.
Original language | American English |
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Pages (from-to) | 4110-4119 |
Number of pages | 10 |
Journal | Vaccine |
Volume | 23 |
Issue number | 32 |
DOIs | |
State | Published - 14 Jul 2005 |
Externally published | Yes |
Keywords
- Cost and cost analysis
- Hepatitis A
- Vaccination