Congenital defects of antithrombin III and proteins C and S during pregnancy. Report of ten cases

Rodrigo Enríquez R.*, Carlos Rondini F., Alvaro Sánchez M., Carmen Montes I., José Andrés Poblete L., Jorge Neira M., Enrique Oyarzún E., Alfredo Germain A.

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We report 10 patients with congenital deficiencies of the natural anticoagulant proteins S, C and antithrombin III. Thirteen of a total of 30 pregnancies were managed at the perinatal branch of our department. We discuss the mechanism of action of these proteins and their role in thrombotic events. We analyze the most frequent thrombotic complications and we discuss the general guidelines for the investigation of a patient with a suspected congenital thrombophilia with special regard to its management during pregnancy, delivery and perinatal outcome.

Translated title of the contributionCongenital defects of antithrombin III and proteins C and S during pregnancy. Report of ten cases
Original languageSpanish
Pages (from-to)171-180
Number of pages10
JournalRevista Medica de Chile
Volume127
Issue number2
StatePublished - Feb 1999
Externally publishedYes

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