Chilean Association of Digestive Endoscopy (ACHED) guidelines for the detection of early gastric cancer and surveillance of gastric premalignant conditions in high-risk populations

Gonzalo Latorre; Alberto Espino; Raúl Araya; Matías Arteaga; Harold Benites-Goñi; María Ester Bufadel; Dacio Cabrera-Hinojosa; Roberto Candia; Julian Cordero; Oscar Corsi; Pablo Cortés; Felipe Donoso; Fabian Emura; Carolina Heredia; Daniel Martínez; Rodrigo Mansilla-Vivar; Leticia Moreira; Felipe Moscoso; María Blanca Piazuelo; Mauricio Pizarro; Diego Reyes; Arnoldo Riquelme; Shailja C. Shah; Felipe Silva; Verónica Silva; Paulina Toledo; Antonio Rollán

doi:10.1016/j.gastrohep.2025.502633

Chilean Association of Digestive Endoscopy (ACHED) guidelines for the detection of early gastric cancer and surveillance of gastric premalignant conditions in high-risk populations

Gonzalo Latorre^*
, Alberto Espino
, Raúl Araya
, Matías Arteaga
, Harold Benites-Goñi
, María Ester Bufadel
, Dacio Cabrera-Hinojosa
, Roberto Candia
, Julian Cordero
, Oscar Corsi
, Pablo Cortés
, Felipe Donoso
, Fabian Emura
, Carolina Heredia
, Daniel Martínez
, Rodrigo Mansilla-Vivar
, Leticia Moreira
, Felipe Moscoso
, María Blanca Piazuelo
, Mauricio Pizarro

Diego Reyes, Arnoldo Riquelme, Shailja C. Shah, Felipe Silva, Verónica Silva, Paulina Toledo, Antonio Rollán

^*Corresponding author for this work

Universidad de los Andes

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Gastric cancer is one of the leading causes of cancer mortality in Chile. To optimize early detection and surveillance of gastric premalignant conditions, the Chilean Association of Digestive Endoscopy (ACHED), together with the Chilean Society of Gastroenterology, updated its 2014 clinical guideline. Using the AGREE II methodology, multidisciplinary working groups conducted systematic reviews in PubMed, Cochrane, and Scielo through December 2024. Recommendations were agreed upon via a Delphi panel (≥80% agreement) and graded according to GRADE, assessing evidence quality and recommendation strength. An expert panel of Chilean and international gastroenterology, endoscopy and pathology specialists reviewed the evidence and reached consensus to issue recommendations for opportunistic gastric cancer screening and surveillance using upper GI endoscopy in adults. These recommendations are feasible to implement in Chile and other Latin American countries with a high incidence of gastric cancer that have the necessary resources available. They complement any future efforts at population screening and aim to improve early detection and prognosis of gastric cancer in high-risk populations.

Original language	English
Article number	502633
Journal	Gastroenterologia y Hepatologia
Volume	49
Issue number	3
DOIs	https://doi.org/10.1016/j.gastrohep.2025.502633
State	Published - Mar 2026

Bibliographical note

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Chile
Endoscopic surveillance
Gastric neoplasms
Helicobacter pylori
OLGA
OLGIM
Quality indicators
Sydney protocol

Access to Document

10.1016/j.gastrohep.2025.502633

Cite this

Latorre, G., Espino, A., Araya, R., Arteaga, M., Benites-Goñi, H., Bufadel, M. E., Cabrera-Hinojosa, D., Candia, R., Cordero, J., Corsi, O., Cortés, P., Donoso, F., Emura, F., Heredia, C., Martínez, D., Mansilla-Vivar, R., Moreira, L., Moscoso, F., Piazuelo, M. B., ... Rollán, A. (2026). Chilean Association of Digestive Endoscopy (ACHED) guidelines for the detection of early gastric cancer and surveillance of gastric premalignant conditions in high-risk populations. Gastroenterologia y Hepatologia, 49(3), Article 502633. https://doi.org/10.1016/j.gastrohep.2025.502633

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title = "Chilean Association of Digestive Endoscopy (ACHED) guidelines for the detection of early gastric cancer and surveillance of gastric premalignant conditions in high-risk populations",

abstract = "Gastric cancer is one of the leading causes of cancer mortality in Chile. To optimize early detection and surveillance of gastric premalignant conditions, the Chilean Association of Digestive Endoscopy (ACHED), together with the Chilean Society of Gastroenterology, updated its 2014 clinical guideline. Using the AGREE II methodology, multidisciplinary working groups conducted systematic reviews in PubMed, Cochrane, and Scielo through December 2024. Recommendations were agreed upon via a Delphi panel (≥80\% agreement) and graded according to GRADE, assessing evidence quality and recommendation strength. An expert panel of Chilean and international gastroenterology, endoscopy and pathology specialists reviewed the evidence and reached consensus to issue recommendations for opportunistic gastric cancer screening and surveillance using upper GI endoscopy in adults. These recommendations are feasible to implement in Chile and other Latin American countries with a high incidence of gastric cancer that have the necessary resources available. They complement any future efforts at population screening and aim to improve early detection and prognosis of gastric cancer in high-risk populations.",

keywords = "Chile, Endoscopic surveillance, Gastric neoplasms, Helicobacter pylori, OLGA, OLGIM, Quality indicators, Sydney protocol",

author = "Gonzalo Latorre and Alberto Espino and Ra{\'u}l Araya and Mat{\'i}as Arteaga and Harold Benites-Go{\~n}i and Bufadel, \{Mar{\'i}a Ester\} and Dacio Cabrera-Hinojosa and Roberto Candia and Julian Cordero and Oscar Corsi and Pablo Cort{\'e}s and Felipe Donoso and Fabian Emura and Carolina Heredia and Daniel Mart{\'i}nez and Rodrigo Mansilla-Vivar and Leticia Moreira and Felipe Moscoso and Piazuelo, \{Mar{\'i}a Blanca\} and Mauricio Pizarro and Diego Reyes and Arnoldo Riquelme and Shah, \{Shailja C.\} and Felipe Silva and Ver{\'o}nica Silva and Paulina Toledo and Antonio Roll{\'a}n",

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Latorre, G, Espino, A, Araya, R, Arteaga, M, Benites-Goñi, H, Bufadel, ME, Cabrera-Hinojosa, D, Candia, R, Cordero, J, Corsi, O, Cortés, P, Donoso, F, Emura, F, Heredia, C, Martínez, D, Mansilla-Vivar, R, Moreira, L, Moscoso, F, Piazuelo, MB, Pizarro, M, Reyes, D, Riquelme, A, Shah, SC, Silva, F, Silva, V, Toledo, P & Rollán, A 2026, 'Chilean Association of Digestive Endoscopy (ACHED) guidelines for the detection of early gastric cancer and surveillance of gastric premalignant conditions in high-risk populations', Gastroenterologia y Hepatologia, vol. 49, no. 3, 502633. https://doi.org/10.1016/j.gastrohep.2025.502633

Chilean Association of Digestive Endoscopy (ACHED) guidelines for the detection of early gastric cancer and surveillance of gastric premalignant conditions in high-risk populations. / Latorre, Gonzalo; Espino, Alberto; Araya, Raúl et al.
In: Gastroenterologia y Hepatologia, Vol. 49, No. 3, 502633, 03.2026.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Chilean Association of Digestive Endoscopy (ACHED) guidelines for the detection of early gastric cancer and surveillance of gastric premalignant conditions in high-risk populations

AU - Latorre, Gonzalo

AU - Espino, Alberto

AU - Araya, Raúl

AU - Arteaga, Matías

AU - Benites-Goñi, Harold

AU - Bufadel, María Ester

AU - Cabrera-Hinojosa, Dacio

AU - Candia, Roberto

AU - Cordero, Julian

AU - Corsi, Oscar

AU - Cortés, Pablo

AU - Donoso, Felipe

AU - Emura, Fabian

AU - Heredia, Carolina

AU - Martínez, Daniel

AU - Mansilla-Vivar, Rodrigo

AU - Moreira, Leticia

AU - Moscoso, Felipe

AU - Piazuelo, María Blanca

AU - Pizarro, Mauricio

AU - Reyes, Diego

AU - Riquelme, Arnoldo

AU - Shah, Shailja C.

AU - Silva, Felipe

AU - Silva, Verónica

AU - Toledo, Paulina

AU - Rollán, Antonio

PY - 2026/3

Y1 - 2026/3

N2 - Gastric cancer is one of the leading causes of cancer mortality in Chile. To optimize early detection and surveillance of gastric premalignant conditions, the Chilean Association of Digestive Endoscopy (ACHED), together with the Chilean Society of Gastroenterology, updated its 2014 clinical guideline. Using the AGREE II methodology, multidisciplinary working groups conducted systematic reviews in PubMed, Cochrane, and Scielo through December 2024. Recommendations were agreed upon via a Delphi panel (≥80% agreement) and graded according to GRADE, assessing evidence quality and recommendation strength. An expert panel of Chilean and international gastroenterology, endoscopy and pathology specialists reviewed the evidence and reached consensus to issue recommendations for opportunistic gastric cancer screening and surveillance using upper GI endoscopy in adults. These recommendations are feasible to implement in Chile and other Latin American countries with a high incidence of gastric cancer that have the necessary resources available. They complement any future efforts at population screening and aim to improve early detection and prognosis of gastric cancer in high-risk populations.

AB - Gastric cancer is one of the leading causes of cancer mortality in Chile. To optimize early detection and surveillance of gastric premalignant conditions, the Chilean Association of Digestive Endoscopy (ACHED), together with the Chilean Society of Gastroenterology, updated its 2014 clinical guideline. Using the AGREE II methodology, multidisciplinary working groups conducted systematic reviews in PubMed, Cochrane, and Scielo through December 2024. Recommendations were agreed upon via a Delphi panel (≥80% agreement) and graded according to GRADE, assessing evidence quality and recommendation strength. An expert panel of Chilean and international gastroenterology, endoscopy and pathology specialists reviewed the evidence and reached consensus to issue recommendations for opportunistic gastric cancer screening and surveillance using upper GI endoscopy in adults. These recommendations are feasible to implement in Chile and other Latin American countries with a high incidence of gastric cancer that have the necessary resources available. They complement any future efforts at population screening and aim to improve early detection and prognosis of gastric cancer in high-risk populations.

KW - Chile

KW - Endoscopic surveillance

KW - Gastric neoplasms

KW - Helicobacter pylori

KW - OLGA

KW - OLGIM

KW - Quality indicators

KW - Sydney protocol

UR - https://www.scopus.com/pages/publications/105028197348

U2 - 10.1016/j.gastrohep.2025.502633

DO - 10.1016/j.gastrohep.2025.502633

M3 - Article

C2 - 41344434

AN - SCOPUS:105028197348

SN - 0210-5705

VL - 49

JO - Gastroenterologia y Hepatologia

JF - Gastroenterologia y Hepatologia

IS - 3

M1 - 502633

ER -

Chilean Association of Digestive Endoscopy (ACHED) guidelines for the detection of early gastric cancer and surveillance of gastric premalignant conditions in high-risk populations

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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