Chikungunya, enfermedad emergente en América Latina. Descripción de los primeros casos en Chile

Translated title of the contribution: Chikungunya, emerging disease in Latin America. Description of the first cases in Chile

Cecilia Perret Pérez*, Cecilia Vizcaya, Thomas Weitzel, Reinaldo Rosas, Jeannette Dabanch, Constanza Martínez

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background: Chikungunya (CHIK) was introduced in The Americas in 2013, spreading rapidly. In 2014, the first imported case was diagnosed in Chile. Aim: To identify patients with clinical suspicion of CHIK and describe their clinical and laboratory characteristics. Patients and Methods: Patients with suspected CHIK were enrolled. All were confirmed by PCR, IgM or IgG CHIK. A structured survey was applied, which included demographic questions, travel characteristics, clinical manifestations, and laboratory results. Results: 21 patients were enrolled and CHIK was confirmed in 16, who were further analyzed; 12 were female (75%), average age 39 years (27- 52). The Caribbean and South Americawere the most frequent sites of exposure. In 63%, the initial symptom was arthralgia. Most frequent symptoms were myalgias, malaise (both 100%), fever, and polyarthralgia (both 94%). The median duration of arthralgias was 90 days (3-262); in 53% arthralgias lasted ≥ 3 months. Main joints involved were ankles, hands, and wrists; 87% reported invalidating pain. Arthritis lasted longer in men than in women (p < 0.001). 38% of patients presented lymphopenia and one patient mild thrombocytopenia. Two patients required hospitalization, one with severe headaches, the other with acute pyelonephritis. Conclusions: Chikungunya should be suspected in returning travelers presenting with fever and severe polyarthralgia. Travelers to endemic areas should apply prevention measures to avoid mosquito bites.

Translated title of the contributionChikungunya, emerging disease in Latin America. Description of the first cases in Chile
Original languageSpanish
Pages (from-to)413-419
Number of pages7
JournalRevista Chilena de Infectologia
Volume35
Issue number4
DOIs
StatePublished - Aug 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2018, Sociedad Chilena de Infectologia. All rights reserved.

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